CellCept

Generic name: Mycophenolate.

CellCept is an immunosuppressant. It prevents the body from rejecting transplanted organs. It provides for the prophylaxis of organ rejection in patients receiving allogeneic cardiac transplants.

Quick Facts About CellCept

Purpose

Used after kidney organ transplant to prevent rejection of transplanted kidney by suppressing the body’s immune system.

CellCept Dosage

CellCept is always prescribed with prednisone or another steroid and cyclosporine (Sandimmune). Take at the same time every day on an empty stomach, at least 1 hour before or 2 hours after meals. Handle capsules with care; do not open or crush capsules. Avoid inhaling powder or contact with skin or mucous membranes inside your mouth or nose. Thoroughly wash with soap and water if contact occurs. If powder gets in eyes, wash thoroughly with water. Maintain good oral hygiene during CellCept therapy.

  • Usual adult dose: dose is determined to suit individua needs. 2 to 3 grams per day divided into 2 doses.
  • Usual child dose: not generally prescribed for children
  • Missed dose: take as soon as possible, unless almos: time for next dose. In that case, do not take missec dose; go back to regular schedule. Do not double doses Inform your doctor if more than 2 consecutive doses are missed.

CellCept Side Effects

Overdose symptoms:

coma, delirium, increased  severity of side effects. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, acne, anemia, back pain, blood infection, breathing difficulty, bronchitis, changes in blood potassium levels, chest pain, constipation, diarrhea, dizziness, genera, pain, headache, high blood cholesterol, high blood sugar, hypertension, infections (back or side pain, chills, cough, fever, hoarseness, sore throat, trouble urinating), low blood phosphate levels, kidney damage, nausea, oral fungus infection, pneumonia, rash, reduced white-blood-cell and platelet counts, sleeplessness, swelling of arms and legs, tremors, urinary tract problems, vomiting, weakness.

Less common CellCept side effects: abdominal or facia; swelling, angina pain, anxiety, appetite loss, asthma-bleeding, cardiovascular disorders, cataracts, conjunctivitis, cysts, depression, dizziness when rising from a sitting or lying position, double vision, frequent or painful urination, gas, gum irritation or enlargement, hair loss, heart palpitations, hernia, impotence, itching, joint or muscle pain, leg cramps, liver irritation, low blood pressure, mouth ulcer pelvic pain, “pins and needles” in hands or feet, pyelonephritis, sinus irritation, skin bruising, skin ulcer, stiff muscles, stomach irritation or bleeding, stuffy or runny nose, sweating. Rare side effects: chicken pox or shingles, fungus infection, herpes, Pneumocystis and other opportunistic infections.

Interactions

Inform your doctor before combining CellCept with:

acyclovir (Zorivax); aspirin; immune-system drugs such as azathioprine (Imuran) and probenecid (Benemid, Benuryl, or Probalan); phenytoin (Dilantin); theophylline (Theo-Dur).

CellCept and aluminum/magnesium antacids should be taken at least one hour apart. 

Special Cautions

If pregnant or planning to become pregnant, inform your ? doctor before treatment. Can cause serious injury to a fetus. Must have a negative pregnancy test I week before treatment is started, and avoid pregnancy (either through abstinence or use of 2 contraceptive methods) up to 6 weeks after CellCept therapy is completed. Doctor may recommend that an accidental pregnancy while taking CellCept be terminated. Appears in breast milk; could affect a nursing infant

Seniors may be prescribed a lower dose.

Not generally recommended for children.

  • Doctor will monitor levels of CellCept to prevent toxicity due to overdosing or organ rejection due to underdosing.
  • At increased risk for infection and malignancies, including skin cancer and lymph system cancer.
  • High doses of CellCept may result in liver and kidney damage. Doctor may lower dosage or allow your body to reject a transplanted organ rather than give high doses of CellCept.
  • May cause hypertension (high blood pressure Closely monitor blood pressure.
  • Inform your doctor before taking if you have stomach or intestinal disease. CellCept therapy may aggravate bleeding.
  • May result in severe reduction of white-blood-cell count. Inform your doctor immediately if symptoms of viral infection appear. Closely monitor serious side effects: blood in urine, confusion, convulsions difficulty breathing, fever, irregular heartbeat, nervousness, numbness or tingling in hands, feet, or lips, severe stomach pain with nausea, sore throat, tiredness, unusual bruising or bleeding, weakness.
  • Maintain good dental hygiene while taking medication to avoid dental infection. Use extra care when brushing and flossing and see dentist regularly.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or CellCept side effects, please contact your healthcare provider.