Gabitril


Generic name: Tiagabine.

Gabitril is an anticonvulsant. It is thought to work by enhancing the activity of GABA, the major inhibitory neurotransmitter in slowing the nerve function that leads to seizures. 

Quick Facts About Gabitril

Purpose

Used to treat partial seizures in people with epilepsy.

Gabitril Dosage

Take exacdy as prescribed, with meals. Absorbed more quickly with low-fat meals. Do not change dose or discontinue use without consulting your doctor.

  • Usual adult dose: 4 milligrams once per day. Doctor may increase dose in increments of 4 or 8 milligrams up to a total of 56 milligrams per day. Larger amounts should be divided into 2 to 4 doses per day.
  • Usual child dose: for ages 12-18 — 4 milligrams once per day. Doctor may increase dose in increments of 4 or 8 milligrams up to a total of 32 milligrams per day. Larger amount should be divided into 2 doses per day. Not generally prescribed for children under 12 years.
  • Missed dose: take as soon as possible. If almost time for next dose, take missed dose immediately and spread remaining daily doses over the rest of the day. Do not double doses.

Gabitril Side Effects

Overdose symptoms:

agitation, confusion, depression, difficulty speaking, fainting, hostility, muscle spasm, tiredness, weakness. Recovery expected within full day of medical treatment If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, diarrhea, difficulty speaking, dizziness, insomnia, nausea, nervousness, pain, poor concentration, rash, sore throat tremor, weakness, vomiting.

Less common Gabitril side effects: agitation, cough, depression, difficulty walking, emotional upset, flushing, forgetfulness, hostility, itching, mouth sores, “pins and needles” in hands and feet, rolling of eyeballs.

Interactions

Inform your doctor before combining Gabitril with:

central nervous system depressants (CNCs); other medications for seizure control such as barbiturates, carbamazepine (Tegretol), phenytoin (Dilantin), phenobarbital (Solfoton), and valproate (Depakote).

Do not combine alcohol with this medication; may intensify the depressive effects of alcohol. 

Special Cautions

May cause fetql damage. If pregnant or planning to become pregnant inform your doctor immediately. Appears in breast milk; could affect a nursing infant

No special precautions apply to seniors.

Not generally recommended for children under 12 years.

  • Use with caution if you have a history of liver disease, even moderate liver disease. Doctor may lower dose.
  • Inform your doctor immediately if you experience changes in vision, extreme weakness, rash, or any other unusual or severe side effects. Doctor may decrease dose or discontinue treatment.
  • May cause dizziness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires mental alertness until adjusted to medication.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Gabitril side effects, please contact your healthcare provider.