Mexitil

Generic name: Mexiletine hydrochloride.

Mexitil is an anti-arrhythmic. It alleviates cardiac arrhythmias by alternating nerve impulses in the heart. 

Quick Facts About Mexitil

Purpose

Used to treat severe irregular heartbeat.

Mexitil Dosage

Take with food or antacid, exactly as prescribed.

  • Usual adult dose: 200 milligrams every 8 hours, adjusted by your doctor by 50 or 100 milligrams up or down every 2 to 3 days. Doctor may increase dosage to up to 1,200 milligrams per day. For fast relief — 400 milligrams followed by 200 milligrams in 8 hours. Effects will be apparent within 30 minutes to 2 hours. For severe kidney disease — usually prescribed lower doses. At dosage level of 300 milligrams or less, and if medication is tolerated well, doctor will prescribe 12-hour dosage schedule. For seniors — dosage adjusted according to individual needs. Mexitil treatment usually starts in the hospital.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, up to 4 hours past regular schedule. Otherwise, do not take missed dose; go back to regular schedule. Do not double doses.

Mexitil Side Effects

Overdose symptoms:

low  blood pressure, nausea, seizures, slow heartbeat, tingling or pins and needles. If you suspect an overdose, immediately seek medical attention.

Overdose may be fatal.

More common side effects: blurred vision, changes in sleep habits, chest pain, constipation, depression, diarrhea, difficult or labored breathing, dizziness, headache, heartburn, light-headedness, nausea, nervousness, numbness, poor coordination, rash, swelling due to fluid retention, throbbing heartbeat, tingling or pins and needles, tremors, upset stomach, vision changes, vomiting.

Less common Mexitil side effects: abdominal pain or cramps, angina (crushing chest pain), appetite changes, behavior changes, bleeding from the stomach, confusion, congestive heart failure, decreased sex drive, depression, difficulty swallowing, difficulty urinating, dry mouth, dry skin, excessive perspiration, fainting, fatigue, fever, hallucinations, hair loss, hepatitis, hiccups, high blood pressure, hot flashes, impotence, joint pain, loss of consciousness, low or down every 2 to 3 days. Doctor may increase dosage to up to 1,200 milligrams per day. For fast relief — 400 milligrams followed by 200 milligrams in 8 hours. Effects will be apparent within 30 minutes to 2 hours. For severe kidney disease — usually prescribed lower doses. At dosage level of 300 milligrams or less, and if medication is tolerated well, doctor will prescribe 12-hour dosage schedule. For seniors — dosage adjusted according to individual needs. Mexitil treatment usually starts in the hospital.

Interactions

Inform your doctor before combining Mexitil with:

antacids such as Maalox, caffeine products such as No-Doz, cimetidine (Tagamet), other anti-arrhythmic medications such as Norpace and Quinidex, phenobarbital, phenytoin (Dilantin), rifampin (Rifadin), theophylline (Theo-Dur).

No known food/other substance interactions.

Special Cautions

If pregnant or planning to become pregnant inform your doctor immediately. Appears in breast milk; could affect a nursing infant

Dosage adjusted according to individual needs for seniors. Elderly patients should be monitored during Mexitil therapy.

Not generally prescribed for children.

  • Doctor will monitor heartbeat to assure Mexitil is having desired effect.
  • Should not be used if you have heart failure, heart block that has not been corrected with a pacemaker, structural heart disease, or a recent heart attack.
  • May be prescribed with a heart block condition and pacemaker, with ongoing monitoring.
  • Prescribed with caution if you have liver disease or abnormal liver function due to congestive heart failure.
  • Talk with your doctor about your diet — changing pH (acid or alkaline content) of your urine can change the Mexitil excretion from your body.
  • Doctor should monitor for blood disorders; you are at risk while taking Mexitil.
  • Use cautiously if you have a seizure disorder.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Mexitil side effects, please contact your healthcare provider.