Mirapex

Generic name: Pramipexole.

Mirapex is a dopamine agonist. It is thought to work stimulating dopamine receptors in the brain.  

Quick Facts About Mirapex

Purpose

Used to treat early and advanced Parkinson’s disease.

Mirapex Dosage

Take exactly as prescribed. Take on an empty stomach unless nausea occurs. In that case, take with food.

  • Usual adult dose: initially — 0.125 milligram 3 times per day. Doctor will increase dose depending on reaction up to no more than 4.5 milligrams per day.
  • Usual child dose: Not prescribed for children.
  • Missed dose: take immediately. Space remaining doses evenly over the rest of the day. Go back to regular schedule the next day. Do not double doses.

Mirapex Side Effects

Overdose symptoms:

none reported; however, symptoms are likely to be severe side effects. If you suspect an overdose, immediately seek medical attention.

More common side effects: early Parkinson’s disease — constipation, hallucinations, insomnia, nausea, tiredness. Advanced Parkinson’s disease — abnormal movements, dizziness or fainting when rising from sitting or lying position, hallucinations, insomnia, muscle rigidity, tremors.

Less common Mirapex side effects: early Parkinson’s disease — appetite loss, confusion, difficulty swallowing, dizziness, fever, general feeling of ill health, loss of muscle tone, loss of sex drive or impotence, memory loss, muscle spasms, reduced sensation of touch, restlessness or pacing, swelling, vision problems, weakness, weight loss. Advanced Parkinson’s disease — accidental injury, breathing difficulty, chest pain, confusion, constipation, dizziness, delusions and paranoia, dry mouth, general feeling of ill health, memory loss, muscle spasms, pneumonia, rash, restlessness or pacing, runny nose, sleeping problems, swelling, tiredness, unusual dreams or thoughts, urinary infection or problems, vision problems.

Interactions

Inform your doctor before combining Mirapex with:

calcium channel blockers such as diltiazem (Cardizem or Dilacor), verapamil (Isoptin); cimetidine (Tagamet); other antiparkinsonian drugs including levodopa (Dopar or Larodopa); phenothiazine tranquilizers or other tranquilizers such as haloperidol, metoclopramide, thioxanthene, and other drugs that antagonize the effects of dopamine; quinidine (Quinaian or Quinora); quinine (Quindan); ranitidine; sleeping pills and other nervous system depressants; triamterene (found in Dyazide).

Do not drink alcohol while taking Mirapex.

Special Cautions

Effects of Mirapex on pregnant women and nursing f mothers not known. If pregnant, planning to become pregnant, or breastfeeding, inform your doctor immediately.

Seniors may experience difficulty clearing Mirapex if kidney problems exist.

Not prescribed for children.

  • Contact your doctor if you experience hallucinations or other unusual symptoms, including changes in vision.
  • May cause low blood pressure. Use caution when rising from a sitting or lying position to avoid dizziness or fainting.
  • Monitor for high fever, confusion, or breathing problems if taking other antiparkinsonians in combination with Mirapex.
  • Use caution when driving a car or operating dangerous machinery if combining Mirapex with alcohol or other central nervous system depressants.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Mirapex side effects, please contact your healthcare provider.