Parlodel

Generic name: Bromocriptine mesylate.

Parlodel is a dopamine agonist and antiparkinsonism agent. It replaces the dopamine that is diminished in the brains of Parkinson’s patients, and blocks the action of prolactin, a milk production hormone. 

Quick Facts About Parlodel

Purpose

Must take with food in your stomach. Take the first dose lying down, as you may experience dizziness or faint. Full effects of this medication become apparent after a few weeks; do not stop medication unless directed by your doctor.

Parlodel Dosage

Take on

  • Usual adult dose: to prevent milk production after delivery — 1 tablet 2 times per day for 14 days, up to 21 days maximum. For excess prolactin hormone (excessive milk production, menstrual problems, pituitary gland tumors) — 1/2 to 1 tablet daily. Doctor may add a tablet every 3 to 7 days until correct dose is determined (longer term dose ranges from 2.5 to 15 milligrams per day). For growth hormone overproduction — 1/2 to 1 tablet with food at bedtime for 3 days (20 to 30 milligrams per day, not to exceed 100 milligrams per day). For Parkinson’s disease — 1/2 tablet 2 times per day with meals. Doctor may increase dose by 1 tablet every 14 to 28 days. Usually taken with levodopa.
  • Usual child dose: follow doctor’s instructions carefully for children 15 years and older.
  • Missed dose: take as soon as possible if within 4 hours of missed dose. Otherwise, do not take missed dose; go back to regular schedule. Do not double doses.

Parlodel Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal cramps or discomfort, confusion, constipation, depression, diarrhea, dizziness, drop in blood pressure, drowsiness, dry mouth, fainting, fatigue, hallucinations (especially in Parkinson’s patients), headache, inability to sleep, indigestion, light-headedness, loss of appetite, loss of coordination, nasal congestion, nausea, shortness of breath, uncontrolled body movement, vertigo, visual disturbance, vomiting, weakness.

Less common Parlodel side effects: abdominal bleeding, anxiety, difficulty swallowing, frequent urination, heart attack, inability to hold urine, inability to urinate, nightmares, nervousness, rash, seizures, splotchy skin, stroke, swelling or fluid retention in feet and ankles, twitching of eyelids. Rare side effects: abnormal heart rhythm, blurred vision or temporary blindness, cold feet, fast or slow heartbeat, hair loss, heavy headedness, increase in blood pressure, lower back pain, muscle cramps, muscle cramps in feet and legs, numbness, pale face, paranoia, prickling or tingling, reduced tolerance to cold, severe or continuous headache, shortness of breath, sluggishness, tingling of ears or fingers.

Interactions

Inform your doctor before combining Parlodel with:

blood pressure medications such as Aldomet and Catapres; erythromycin (E.E.S. or ERYC); metoclopramide (Reglan); oral contraceptives; other ergot derivatives such as Hydergine; progesterone (Provera). Medications used for psychotic conditions such as Haldol and Thorazine and the other phenothiazines inhibit the action of Parlodel.

Do not drink alcohol during Parlodel therapy; can cause blurred vision, chest pain, headache, confusion, and other problems. 

Special Cautions

If pregnant or planning to become pregnant inform your doctor immediately. Should not be used by women who are breastfeeding, as it prevents the flow of milk.

No special precautions apply to seniors.

Not generally prescribed for children under 15 years. Follow doctor’s instructions carefully for children 15 years and older.

  • Women not wanting to become pregnant during Parlodel therapy should use a “barrier” method of contraception. Do not use oral contraceptives; they prevent Parlodel from working properly.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Should not use if you have: high blood pressure that is not being treated, or toxemia of pregnancy, or if allergic to this or ergot alkaloid medications such as Bellergal-S or Caftergot.
  • Doctor should check pituitary gland before Parlodel therapy.
  • Inform your doctor before taking Parlodel if you have kidney or liver disease, or abnormal heart rhythm caused by heart attack.
  • Stopping Parlodel may cause rapid regrowth of tumor related to endocrine problems.
  • Immediately notify your doctor if you experience hallucinations, confusion, and low blood pressure or severe persistent headache.
  • If you observe persistent runny nose with watery discharge, contact your doctor.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Parlodel side effects, please contact your healthcare provider