Tigan

Generic name: Trimethobenzamide hydrochloride.

Other brand names: Tebamide Suppositories, Tegamide, T-Gen, Ticon, Tiject-20, Trimazide.

Tigan is in anti-emetic. It is thought to act by inhibiting impulses to the vomiting center in the brain.

Quick Facts About Tigan

Purpose

Used to control nausea and vomiting.

Tigan Dosage

Take exactly as prescribed. If using suppository and it is too soft, can chill in refrigerator for approximately 30 minutes or run cold water over suppository while still in the wrapper. Insert suppository well up into rectum.

  • Usual adult dose: capsules — one 250-milligram capsule taken 3 or 4 times per day. Suppositories — 1 suppository (200 milligrams) inserted rectally 3 or 4 times per day.
  • Usual child dose: capsules — for children weighing 30 to 90 pounds — one or two 100-milligram capsules taken 3 or 4 times per day. Suppositories — for children weighing under 30 pounds — 1/2 suppository (100 milligrams) inserted rectally 3 or 4 times per day. For children weighing 30 to 90 pounds — 1/2 to one 200-milligram suppository inserted rectally 3 or 4 times per day. Pediatric suppositories — for children weighing under 30 pounds — 1 suppository (100 milligrams) inserted rectally 3 or 4 times per day. For children weighing 30 to 90 pounds — 1 or 2 suppositories (100 to 200 milligrams) rectally 3 or 4 times per day.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Tigan Side Effects

Overdose symptoms:

allergic-type skin reactions, blurred vision, coma, convulsions, depression, diarrhea, disorientation, dizziness, drowsiness, headache, muscle cramps, severe muscle spasm, tremors, yellowed eyes and skin.

Side effects: allergic-type skin reactions, blurred vision, coma, convulsions, depression, diarrhea, disorientation, dizziness, drowsiness, headache, muscle cramps, severe muscle spasm, tremors, yellowed eyes and skin.

No known less common or rare Tigan side effects.

Interactions

Inform your doctor before combining Tigan with:

central nervous system medications such as phenothiazines (tranquilizers and anti-emetics); barbiturates such as phenobarbital; medications derived from belladonna such as Donnatal; if you are dehydrated; or have a severe disease with fever, inflammation of the stomach, intestines, or brain.

Avoid using alcohol with Tigan.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Tigan appears in breast milk.

Seniors should use with caution if you have severe illness with high fever, brain inflammation, stomach or intestinal inflammation, or dehydration.

Follow doctor’s instructions carefully for children. Not for use to treat simple vomiting in children; used for prolonged vomiting due to a known disease. Use with caution if you have severe illness with high fever, brain inflammation, stomach or intestinal inflammation, or dehydration. May be link to Reye’s syndrome if used to treat viral illnesses in children. Do not use suppositories in premature or newborn infants.

  • Do not take if sensitive to. Do not use suppositories if allergic to benzocaine or other local anesthetics.
  • May impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • If you have a weakened condition, use with caution if you have severe illness with high fever, brain inflammation, stomach or intestinal inflammation, or dehydration.
  • Antinausea effects may mask conditions such as appendicitis or overdose of other medications.

Note:

HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Tigan side effects, please contact your healthcare provider