Generic name: Methyldopa.

Aldomet is an antihypertensive. It is thought to act on the central nervous system to prevent the release of chemicals responsible for maintaining high blood pressure.

Quick Facts About AldometAldomet-1


Used to treat high blood pressure.

Aldomet Dosage

Take exactly as prescribed. Aldomet must be taken » on a regular basis to be effective; try not to miss any doses. It may take several weeks before any benefit is observed.

  • Usual adult dose: 250 milligrams 2 or 3 times per day in the first 48 hours of treatment. Maintenance dose is 500 milligrams per day divided into 2 to doses. Maximum dose is usually 3 grams.
  • Usual child dose: 10 milligrams per 2.2 pounds of body weight daily, divided into 2 to 4 doses, adjusted until blood pressure is normal. Maximum daily dose is 65 milligrams per 2.2 pounds of body weight or 3 grams, whichever is less.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Aldomet Side Effects

Overdose symptoms:

bloating, constipation, diarrhea, dizziness, extreme drowsiness, gas, light-head-edness, nausea, severely low blood pressure, slow heartbeat, vomiting, weakness. If you suspect an overdose, immediately seek medical attention.

More common side effects: drowsiness at beginning of therapy, fluid retention or weight gain, headache, weakness.

Less common Aldomet side effects: anemia, Beli’s palsy (paralysis of the face), bloating, blood disorders, breast development in males, breast enlargement, changes in menstruation, chest pain, congestive heart failure, constipation, decreased mental ability, decreased sex drive, depression, diarrhea, dizziness when standing up, dry mouth, fever, gas, hepatitis, impotence, inflammation of the large intestine, inflammation of the pancreas, inflammation of the salivary glands, involuntary movements, joint pain, light-headedness, liver disorders, milk production, muscle pain, nasal stuffiness, nausea, nightmares, parkinsonism (tremors, shuffling walk, stooped posture, muscle weakness), rash, slow heartbeat, sore or “black” tongue, tingling or pins and needles, vomiting, yellow eyes and skin.


Inform your doctor before combining Aldomet with:

Dextroamphetamine (Dexedrine), Imipramine (Tofranil), Lithium (Lithonate), other high blood pressure drugs, Phenylpropanolamine (decongestant used Aldomet  in Comprex, Entex LA, and others), Propranolol (Inderal), Tolbutamide (Orinase).

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Using Aldomet during pregnancy is relatively safe. Appears in breast milk; could affect a nursing infant.

Seniors: octor will vary dosage levels according to individual needs.

Follow doctor’s instructions carefully for children.

  • Do not take if you have liver disease or cirrhosis, or developed liver disease from taking Aldomet.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Should not take if sensitive to or had allergic reaction to Aldomet, or if taking oral suspension Aldomet and had an allergic reaction to sulfites.
  • Before starting Aldomet therapy, your doctor should monitor your liver function.
  • May develop fever, jaundice within first 2 to 3 months of Aldomet therapy. If this occurs, stop taking immediately, contact your doctor.
  • Extended use may cause hemolytic anemia, a blood disorder that destroys red blood cells.
  • May experience elevated blood pressure after dialysis treatments.
  • Before medical or dental surgery, tell your doctor or dentist you are taking this drug.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Aldomet side effects, please contact your healthcare provider.