Generic name: Amlexanox.

Aphthasol is a skin-ulcer treatment. It seems to accelerate the healing of aphthous ulcers by inhibiting the formation and/or release of factors involved in the body’s inflammatory response. 

Quick Facts About Aphthasol


Used to treat mouth ulcers in people with normal immune systems.

Zofran Dosage

Clean teeth and mouth. Squeeze small amount of paste (1/4 inch) onto finger and apply gently to each ulcer. Thoroughly wash hands before and after applying. Wash eyes thoroughly if they come into contact with paste. Take as soon as mouth ulcer(s) begin to appear and continue usage until fully healed. If symptoms are not alleviated within 10 days, inform your doctor.

  • Usual adult dose: 1/4 inch applied to each mouth ulcer 4 times per day — after breakfast, lunch, and dinner and at bedtime.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Aphthasol Side Effects

Overdose symptoms:

none reported; however, swallowing entire tube may cause diarrhea, nausea, upset stomach, and vomiting. If you suspect an overdose, immediately seek medical attention.

No common side effects reported.

Less common Aphthasol side effects: burning after application, pain, stinging. Rare side effects: diarrhea, mouth irritation, nausea.


No known  Aphthasol drug interactions.

Do not allow medication to interact in the mouth with food (wash mouth thoroughly before application and refrain from eating immediately after). 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Should not use medication if allergic to Aphthasol of any of its ingredients.
  • May cause pain, stinging, or burning of the mouth. If rash or inflammation occurs, discontinue use.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Aphthasol side effects, please contact your healthcare provider.