Generic name: Irbesartan

Avapro is an angiotensin II receptor antagonist, a new class of blood pressure medications. It works by preventing the angiotensin II hormone from constricting the blood vessels, which usually raises blood pressure. 

Quick Facts About Avapro


Used to control hypertension (high blood pressure). Effectiveness increases when combined with a thiazide-type diuretic. Can be used with other high blood pressure medications.

Avapro Dosage

Take exactly as prescribed. Take at approximately the same time every day, with or without food.

  • Usual adult dose: initially — 150 milligrams once daily. Doctor may increase dosage to 300 milligrams per day. For people suffering from dehydration or salt depletion — 75 milligrams per day.
  • Usual child dose: not generally prescribed for children under 18 years.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Avapro Side Effects

Overdose symptoms:

none reported; however, symptoms would probably include low blood pressure and rapid heartbeat or very slow heartbeat. If you suspect an overdose, immediately seek medical attention.

More common side effects: No known common side effects.

Less common Avapro side effects: abdominal pain, anxiety, back pain, diarrhea, fatigue, muscle pain, nausea, rapid heartbeat rash, runny nose, upper respiratory infection (cough, fever, sore throat), upset stomach or heartburn, urinary infection, vomiting. Rare side effects: fainting, low blood pressure.


No known Avapro drug interactions.

Do not combine Avapro with over-the-counter diet pills, decongestants, or stimulants. 

Special Cautions

Avapro can cause serious injury to a fetus when used during the second or third trimesters. If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not recommended for children.

  • Do not discontinue use of Avapro without consulting your doctor, even if you don’t feel well. Benefits of medication may take several weeks to appear.
  • May cause low blood pressure, especially when used in combination with a diuretic. Inform your doctor immediately if you become light-headed or faint; or if you experience a severe drop in blood pressure, indicated by dehydration, excessive sweating, severe diarrhea, or vomiting.
  • Use caution when exercising or performing activities in hot weather. Do not drive or operate machinery until adjusted to medication.
  • Follow any special diet your doctor prescribes. It may help control hypertension.
  • Should not be used if sensitive or allergic to Avapro.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Avapro side effects, please contact your healthcare provider.