Generic name: Brinzolamide

Azopt is a carbonic anhydrase inhibitor in the family of sulfa drugs. It lowers pressure in the eye by reducing the production of fluid found in the eye. 

Quick Facts About Azopt


Used to treat glaucoma and ocular hypertension (high pressure inside the eye).

Azopt Dosage

Use exactly as prescribed. Wash hands before and after use, shake bottle thoroughly, and do not touch applicator to your eye or any other surface. Wait at least 10 minutes before applying other eye medications, and at least 15 minutes before inserting soft contact lenses.

  • Usual adult dose: 1 drop in the affected eye 3 times per day (every 8 hours).
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Azopt Side Effects

Overdose symptoms:

none reported; however, if you suspect an overdose, immediately seek medical attention.

More common side effects: blurred vision, drowsiness, dry eye or mouth, eye ache or discomfort, headache, sensation of something in eye, sensitivity to bright light, taste changes.

Less common Azopt side effects: abdominal pain, appetite loss, arthritic pain, back pain, blood diseases, chills, diarrhea, dizziness, fatigue, fever, general feeling of ill health, hair loss, hallucination, hearing loss, itching, nausea, “pins and needles” in hands and feet, rash, ringing in ears, vomiting, weakness, yellowing of skin or whites of eyes.


Inform your doctor before combining Azopt with:

anticonvulsants such as phenytoin (Dilantin); aspirin and other salicylates; ciprofloxacin (Cipro); digitalis preparations such as digoxin (Lanoxin); cyclosporine (Sandimmune); erythromycin; lithium; mecamylamine (Inversine); methenamine (Mendelamine); methotrexate (Rheumatrex); mexiletine (Mexitil); other carbonic anhydrase inhibitors such as acetazolamide (Diazamide and Diamox), dichlorphenamide (Daranide), and methazolamide (MZM and Neptazane); quinidine (Quinalan); sulfonylurea-type antidiabetic drugs; warfarin (Coumadin).

Avoid tobacco and vitamins containing folic acid. Eat potassium-rich foods to decrease potassium loss. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Small amount of medication may appear in bloodstream and breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not prescribed for children.

  • Should not take if sensitive or allergic to sulfa drugs, thiazide and loop diuretics, carbonic anhydrase inhibitors, or sulfonylurea-type oral antidiabetics. Could cause dangerous reaction.
  • Consult with your doctor before undergoing ocular surgery or if you experience an eye infection or trauma.
  • Use with caution if you have: Addison’s disease; cardiovascular disease; diabetes; dizziness or fainting when rising from a sitting or lying position; kidney or liver disease.
  • Effects of Azopt may diminish with time. Doctor should monitor eye pressure regularly and adjust dosage if necessary.
  • May cause blurred vision or drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires mental alertness until adjusted to medication.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Azopt side effects, please contact your healthcare provider.