Generic name: Levobunolol hydrochloride.

Betagan is a beta-adrenergic blocking agent. It works to reduce pressure in the eye. 

Quick Facts About Betagan


Used to treat chronic open-angle glaucoma (increased pressure inside the eye) and ocular hypertension.

Betagan Dosage

Use exactly as prescribed. Taper off use of medication slowly. In the case of overproduction of thyroid hormone, abrupt withdrawal may provoke a rush of the hormone.

  • Usual adult dose: starting dose — 1 drop of Betagan 0.5% in the affected eye(s) 1 time per day. Maintenance dose — 1 or 2 drops of Betagan 0.25% 2 times per day. For more severe glaucoma — doctor may prescribe Betagan 0.5% 2 times per day.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: if taking 1 time per day — take as soon as possible, unless it is the next day. In that case, do not take missed dose; go back to regular schedule. Do not double doses. If taking 2 times per day — take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Betagan Side Effects

Overdose symptoms:

breathing difficulty, heart failure, low blood pressure, and/or slowed heartbeat If you suspect an overdose, immediately seek medical attention.

More common side effects: burning and stinging when applying eye drops, eye inflammation.

Less common Betagan side effects: chest pain, congestive heart failure, depression, diarrhea, difficult or labored breathing, dizziness, fainting, headache, heart palpitations, hives, low blood pressure, nasal congestion, nausea, pins and needles, rash, slow or irregular heartbeat, stroke, temporary heart stoppage, vision problems, weakness, wheezing.


Inform your doctor before combining Betagan with:

calcium-blocking blood pressure medications such as Calan and Cardizem; Digitalis (heart medication Lanoxin); Epinephrine (EpiPen); oral beta-blockers such as Inderal and Tenormin; Reserpine (Serpasil).

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Other beta-blocker medications do appear in breast milk, use with caution if breastfeeding.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not use more than 2 beta-blocker eye medications simultaneously.
    Should not use Betagan if you have: asthma or other respiratory diseases, cardiogenic shock, certain heart irregularities, decreased heart function, diabetes, low blood sugar, severe chronic obstructive lung disease, slow heartbeat.
  • Betagan contains sulfites; monitor for allergic reactions.
  • Inform your doctor you are taking Betagan before surgery that requires anesthesia.
  • Medication may affect other parts of the body; use with caution.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Betagan side effects, please contact your healthcare provider.