Generic name: Bicalutamide.

Casodex is an antiandrogen. It competes with testosterone and other natural androgens (male hormones) by binding to the same places in the body tissue where androgens normally bind.  

Quick Facts About Casodex


Used to treat prostate cancer, which responds to treatments that counteract the effects of androgen or remove the sources of androgen. Always prescribed with a luteinizing hormone-releasing agent such as leuprolide or goserelin.

Casodex Dosage

Take exactly as prescribed at the same time every day. Do not discontinue use without consulting your doctor.

  • Usual adult dose: 50 milligrams once per day, morning or night.
  • Usual child dose: Not prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses Inform your doctor if you miss more than one dose

Casodex Side Effects

Overdose symptoms:

none reported. If you suspect an overdose, immediately seek medical attention.

More common side effects: back pain, breast swelling or pain, constipation, diarrhea, hot flashes, nausea, pain, pelvic pain, weakness.

Less common Casodex side effects: abdominal pain, anemia, blood in urine, bone pain, chest pain, difficulty breathing, flu-like symptoms, headache, high blooc pressure, high blood sugar, impotence, nighttime or painful urination, rash, sweating, swelling in the ankles or lower legs, urinary or other infection, vomiting, and weight loss. Rare side effects: anxiety, arthritis, blood infection, blood in stool, chills, confusion, dehydration, depression, dry mouth, dry skin, feeling the need to urinate, fever, gout, hair loss, heart failure, heart pain, itching, leg cramps, muscle pain, muscle spasm, neck pain, nervousness, rectal bleeding, reduced sex drive, tiredness, and upset stomach.


Inform your doctor before combining Casodex with:

anticoagulant drugs like warfarin. Your doctor may have to adjust dosage.

No known food/other substance interactions.

Special Cautions

Not prescribed for women. However, it is important to note that Casodex could harm the fetus if taken during pregnancy and could affect a nursing infant.

No special precautions apply to seniors.

Not prescribed for children.

  • Casodex treatment should always be started at the same time as a luteinizing hormone-releasing agent such as leuprolide or goserelin. Do not stop either treatment without your doctor’s permission. Do not take if allergic to bicalutamide or any ingredient in the product. May reduce sperm count.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Casodex side effects, please contact your healthcare provider.