Generic name: Cefprozil.

Cefzil is a cephalosporin antibiotic. It interferes with the production of certain biochemicals necessary for bacteria to sustain life. 

Quick Facts About Cefzil


Used to treat mild to moderately severe bacterial infections of the throat, ear, respiratory tract, and skin, such as strep throat, tonsillitis, bronchitis, and pneumonia.

Cefzil Dosage

Take exactly as prescribed; finish taking all medicaidtion. Works faster when taken on an empty stomach, but doctor may suggest taking with food to avoid stomach upset. Shake suspension well before taking; discard unused portion after 14 days.

  • Usual adult dose: for throat and respiratory tract infections — 500 milligrams taken once per day for 10 days. For skin infections — 250 milligrams taken 2 times per day, or 500 milligrams taken 1 or 2 times per day for 10 days. Now available in powdered form.
  • Usual child dose: for children 2 to 12 years — 7.5 milligrams for each 2.2 pounds of body weight, taken 2 times per day for 10 days (for throat infections, skin infections, and tonsillitis). For infants and children 6 months to 12 years — 15 milligrams for each 2.2 pounds of body weight, taken 2 times per day for 10 days (for ear infections). For infants under 6 months — not generally prescribed.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Cefzil Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: nausea.

Less common or rare Cefzil side effects: abdominal pain, confusion, diaper rash, diarrhea, difficulty sleeping, dizziness, genital itching, headache, hives, hyperactivity, nervousness, rash, sleepiness, superinfection (additional infection), vaginal inflammation, vomiting, yellow eyes and skin.


Inform your doctor before combining Cefzil with:

other antibiotics such as Amikin, diuretics such as Edecrin and Lasix, oral contraceptives, Probenecid (Benemid), Propantheline (Pro-Banthine).

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing baby.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children.

  • If allergic to cephalosporins or penicillins, tell your Mbf doctor before taking Cefzil; could result in an extremely severe reaction.
  • If you develop diarrhea, contact your doctor immediately, colitis has been associated with using Cefzil.
  • Doctor should check kidney function before treatment, and monitor while on treatment.
  • Use with caution if: taking a strong diuretic, or if you have had stomach and intestinal disease such as colitis.
  • May need to be treated with another antibiotic if you get a new infection.
  • Can alter urine sugar test results (for diabetes).


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Cefzil side effects, please contact your healthcare provider.