Generic name: Carvedilol.

Coreg is an alpha-beta-adrenergic blocker. It works to reduce the amount of stress put on the heart by reducing the amount of blood pumped with each heartbeat and by decreasing the responsiveness of the heart to various kinds of overstimulation. It also reduces high blood pressure. 

Quick Facts About Coreg


Used to treat heart failure. Unlike other beta-blockers, also safe to treat angina pain, cardiomyopathy, congestive heart failure, and high blood pressure.

Coreg Dosage

Take exactly as prescribed, with food to slow absorption and decrease risk of dizziness. Do not discontinue use without your doctor’s approval.

  • Usual adult dose: for heart failure — 3.125 milligrams 2 times per day for first 2 weeks. Doctor will double dose every 2 weeks, with a maximum dose based on body weight. For people weighing less than 187 pounds — 25-milligram maximum twice per day. For people weighing over 187 pounds — 50-milligram maximum twice per day. For high blood pressure and cardiomyopathy — 6.25 milligrams twice per day, initially. Doctor may increase dose to no more than 25 milligrams twice per day.
  • Usual child dose: not generally prescribed for children under 18 years.
  • Missed dose: take as soon as possible, unless within 4 hours of next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Coreg Side Effects

Overdose symptoms:

very low blood pressure (indicated by dizziness or fainting), heart problems including slow heartbeat and heart attack, breathing difficulties, bronchial spasm, periods of unconsciousness, vomiting. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, back pain, breathing difficulties, diarrhea, dizziness when rising from a sitting or lying position, fatigue, general dizziness, high blood triglyceride levels, insomnia, low blood platelet levels, sleepiness, slow heartbeat, sore throat, swelling of hands and feet, urinary tract infection, viral infection. Coreg side effects are usually mild.

Less common Coreg side effects: abnormal vision, anemia, blood pressure changes, chest pain, decreased blood supply to arms and legs (indicated by cramps, aches, or tiredness in foot, thigh, hip, or buttocks), depression, dry mouth, fainting, headache, heart palpitation, high blood cholesterol, sugar, or uric acid, hot flashes, impotence and decreased sex drive in men, liver irritation, muscular pain, nausea, nervousness, “pins and needles” in hands and feet, ringing in ear, sinusitis, skin rash, sweating, upper respiratory tract infection, upset stomach, vomiting. Rare side effects: angina pain, abnormal heart rhythms, amnesia, asthma, allergy, blood in urine, bronchospasm, changes in potassium levels, confusion, decreased hearing, hair loss, heart failure, increased urination, kidney failure, migraine, neuralgia, sugar in urine, weight gain.


Inform your doctor before combining Coreg with:

blood-pressure-lowering medications such as donidine; calcium channel blockers such as diltiazem (Cardizem and Dilacor) and verapamil (Calan and Isoptin); cimetidine (Tagamet); digitalis glycosides such as digoxin; general anesthesia used in major surgeries; rifampin (Rifadin and Rimactane); torsemide (Demadex).

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Benefits may outweigh risks. Not known if Coreg appears in breast milk; could affect a nursing infant.

Seniors are more likely to develop side effects, especially dizziness. Doctor may prescribe lower dose.

Not generally prescribed for children under 18 years.

  • Coreg may cause liver dysfunction or jaundice. Contact your doctor immediately if you experience loss of appetite, dark urine, itching, unexplained flu-like symptoms, or yellowing of the skin or eyes.
  • Inform your doctor before taking if you have a history of asthma, diabetes, kidney or liver disease, or thyroid problems.
  • Do not discontinue use without the approval of your doctor. Rapid withdrawal may cause breathing difficulties, chest pain, fast or irregular heartbeat, increased sweating.
  • A drop in blood pressure may occur when standing, resulting in dizziness and, rarely, fainting. Sit or lie down when these symptoms occur and avoid driving or hazardous tasks.
  • Contact lens wearers may experience dry eyes.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Coreg side effects, please contact your healthcare provider.