Generic name: Misoprostol.

Cytotec is a synthetic prostaglandin/anti-ulcer agent. It works to relieve and promote the healing of ulcers.

Quick Facts About Cytotec


Used to treat and prevent stomach ulcers in people who take Aspirin and other nonsteroidal anti-in-flammatory medications.

Cytotec Dosage

Take with meals, exactly as prescribed.

  • Usual adult dose: 200 micrograms 4 times per day with food. Take last dose at bedtime. Doctor may adjust down to 100 micrograms if you cannot tolerate higher level.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for the next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Cytotec Side Effects

Overdose symptoms:

abdominal pain, breathing difficulty, convulsions, diarrhea, fever, heart palpitations, low blood pressure, sedation (extreme drowsiness), slowed heartbeat stomach or intestinal discomfort tremors. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal cramps, diarrhea, nausea. Other side effects: constipation, gas, indigestion, headache, heavy menstrual bleeding, menstrual disorder, menstrual pain or cramps, paleness, spotting (between periods), stomach or intestinal bleeding, uterine bleeding, vomiting.

No known less common or rare Cytotec side effects.


No reported Cytotec interactions.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Cytotec can cause miscarriage. Women of childbearing age must take a pregnancy test 2 weeks prior to Cytotec treatment Not known if Cytotec appears in breast milk.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not take if sensitive to or allergic to Cytotec or other prostaglandin medications.
  • May cause uterine bleeding, even in women who have gone through menopause. If you notice any bleeding, notify your doctor.
  • May cause diarrhea. Use with caution if you have inflammatory bowel disease or any other condition in which the loss of fluid would be dangerous. Take Cytotec with food to help prevent diarrhea. Avoid taking magnesium-containing antacids such as Maalox, Digel, and Mylanta. Have ongoing checkups.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Cytotec side effects, please contact your healthcare provider.