Generic ingredients: Propoxyphene napsylate with acetaminophen.

Other brand names: Darvon-N (propoxyphene napsylate), Darvon (propoxyphene hydrochloride), Darvon Compound-65 (propoxyphene hydrochloride, aspirin, caffeine).

Darvocet-N is a narcotic analgesic. It works by altering the response to mild to moderate painful stimuli. 

Quick Facts About Darvocet-N


Used to treat mild to moderate pain, with or without fever — Darvocet-N and Darvon Compound-65. Darvon-N and Darvon used to treat mild to moderate pain.

Darvocet-N Dosage

Take exactly as prescribed to avoid dependence.

  • Usual adult dose: take every 4 hours as needed for pain. Darvocet-N 50 — 2 tablets: Darvocet-N 100 — 1 tablet; Darvon — 1 capsule; Darvon Compound-65 — 1 capsule. Doctor may lower dosage for individuals with kidney or liver problems. Should not exceed more than 6 capsules per day of Darvon or Darvon Compound-65. Seniors — doctor may lengthen time between doses.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Darvocet-N Side Effects

Overdose symptoms:

for propoxyphene — bluish tinge to the skin, coma, convulsions, decreased or difficult breathing to the point of temporary stoppage, decreased heart function, extreme sleepiness, irregular heartbeat, low blood pressure, pinpoint pupils becoming dilated later, stupor. Additional symptoms with Darvocet-N — abdominal pain, excessive sweating, general feeling of illness, kidney failure, liver problems, loss of appetite, nausea, vomiting. Additional symptoms with Darvon Compound-65 — confusion, deafness, excessive perspiration, headache, mental dullness, nausea, rapid breathing, rapid pulse, ringing in the ears, vertigo, vomiting. If you suspect an overdose, immediately seek medical attention.

Extreme overdose may lead to unconsciousness and death.

More common side effects: drowsiness, dizziness, nausea, sedation, vomiting.

Less common Darvocet-N side effects: abdominal pain, constipa-M tion, feelings of elation or depression, hallucinations, headache, kidney problems, light-headedness, liver problems, minor visual disturbances, skin rashes, weakness, yellowed eyes and skin.


Inform your doctor before combining Darvocet-N with:

anticonvulsant medications such as Tegretol (severe neurologic disorders have occurred when taken with Darvocet-N), antidepressant drugs such as Elavil, antihistamines such as Benadryl, muscle relaxants such as Flexeril, narcotic pain relievers such as Demerol, sleep aids such as Halcion, tranquilizers such as Xanax and Valium, warfarin-like drugs such as Coumadin.

Avoid alcohol while taking Darvocet-N; heavy use may cause overdose symptoms. 

Special Cautions

Do not take Darvocet-N if pregnant or planning to become pregnant, or in the last 3 months of pregnancy unless directed by a doctor; may cause temporary drug dependence in newborns. Does appear in breast milk; no adverse effects have been found in nursing infants.

Seniors may be directed by their doctor to lengthen time between doses.

Not generally prescribed for children.

  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • If sensitive to or allergic to Darvocet-N or similar drugs, you should not take.
  • Consult with your doctor before taking Darvocet-N if you have: kidney or liver disease, blood clotting problem, ulcer.
  • Due to association between aspirin and Reye’s syndrome, children and teenagers with chicken pox or flu should not take Darvon Compound-65 unless directed by a doctor.
  • If you have experienced asthma attacks from aspirin, contact your doctor before taking Darvon Compound-65.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Darvocet-N side effects, please contact your healthcare provider.