Generic name: Prednisone.

Other brand names: Liquipred, Meticorten, Orasone, Panasol-S, Prednicen-M, Sterapred.

Deltasone is an adrenocorticosteroid/anti-inflammatory. It works by stimulating the synthesis of enzymes needed to decrease the inflammatory response. 

Quick Facts About Deltasone


Used to treat inflammation and symptoms of several disorders, including rheumatoid arthritis, severe asthma, and a lack of sufficient adrenal hormone. Also used to treat: allergic conditions (severe), blood disorders, certain cancers, connective tissue diseases, eye diseases, flare-ups of multiple sclerosis, fluid retention due to kidney damage, lung diseases, prevention of organ rejection, severe flare-ups of ulcerative colitis or inflammation of the intestines, skin diseases, trichinosis (with complications).

Deltasone Dosage

Take exactly as prescribed. Doctor may suggest taking with meals to prevent peptic ulcers. Consult with doctor before abruptly stopping medication. For long-term therapy, doctor may prescribe alter-nate-day therapy. If on alternate-day therapy, take Deltasone in the morning, with breakfast.

  • Usual adult dose: 5 to 60 milligrams per day, depending on what you are being treated for, and your tolerance to the medication. For multiple sclerosis — 200 milligrams per day for one week. Lower dose may be prescribed if you have: cirrhosis of the liver or underactive thyroid.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: for 1 daily dose — take as soon as possible, unless you remember the next day. In that case, do not take missed dose; go back to regular schedule. For several doses per day — take as soon as possible, then go back to regular schedule. If you remember when it is time to take the next dose, take 2 doses. For every-other-day dose — take as soon as possible (if in the morning), then go back to regular schedule. If you remember in the afternoon, skip the next morning; go back to regular schedule.

Deltasone Side Effects

Overdose symptoms:

long-term use may cause Cushing’s syndrome (moon face, weight gain, high blood pressure, emotional disturbances, growth of facial hair in women). If you suspect an overdose, immediately seek medical attention.

Side effects: Cushing’s syndrome, euphoria, eye problems, fluid retention, high blood pressure, insom-nia, mood changes, personality changes, psychotic behavior, severe depression.

Other potential Deltasone side effects: bone fractures, bulging eyes, convulsions, distended abdomen, face redness, glaucoma, headache, hives and other allergic-type reactions, increased pressure inside eyes or skull, inflamed esophagus or pancreas, irregular menstrual periods, muscle weakness or disease, osteoporosis, peptic ulcer, poor healing of wounds, stunted growth (in children), sweating, thin or fragile skin, vertigo.


Do not get a smallpox vaccination while taking Deltasone.

Inform your doctor before combining Deltasone with:

amphotericin B (Fungizone); aspirin; carbamazepine (Tegretol); cyclosporine (Sandimmune); estrogen drugs such as Premarin; ketoconazole (Nizoral); oral contraceptives; oral medications for diabetes such as Insulin; phenytoin (Dilantin); potent diuretics such as Lasix; rifampin (Rifadin).

No known food/other substance interactions.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Deltasone appears in breast milk.

No special precautions apply to seniors.

Not generally prescribed for children. If prescribed, be aware that Deltasone may stunt growth if taken for a prolonged period.

  • Do not take if sensitive to or had an allergic reaction to Deltasone.
  • Use with extreme caution if you have an eye infection caused by herpes simplex.
  • May experience lowered resistance to infections, or may mask the signs of infection. Immediately inform your doctor if exposed to measles or chicken pox; can be serious or fatal in adults.
  • Should not take if you have a fungus infection throughout your body, such as candidiasis or cryptococcosis.
  • Dormant tuberculosis may be activated by Deltasone. Doctor should prescribe anti-tuberculosis medication if taking Deltasone for a prolonged period.
  • Use with caution if you have: diverticulitis, high blood pressure, kidney disorder, myasthenia gravis, osteoporosis, peptic ulcer, ulcerative colitis.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Deltasone side effects, please contact your healthcare provider.