Generic name: Betamethasone dipropionate.

Other brand names: Alphatrex, Betatrex, Beta-Val, Diprosone, Lotrisone, Maxivate, Teladar, Valisone.

Diprolene is a topical corticosteroid. It interferes with the natural body mechanisms that produce rash, itching or inflammation. 

Quick Facts About Diprolene


Used to treat itchy rashes and other inflammatory skin conditions.

Diprolene Dosage

Apply a thin film, as prescribed. For use on the skin only; keep out of eyes. Use only for the skin condition for which this medication is prescribed. To prevent unwanted side effects, avoid using large amounts over large areas; do not use airtight bandages. Do not use for longer than prescribed.

  • Usual adult dose: cream or ointment — apply thin film 1 or 2 times per day, up to 45 grams per week. Lotion — apply a few drops 1 or 2 times per day, up to 50 milliliters per week, and 14 days. Gel — apply thin layer 1 or 2 times per day, up to 50 grams per week, and 14 days.
  • Usual child dose: not generally prescribed for children under 12 years.
  • Missed dose: apply as soon as possible, unless almost time for next dose. In that case, do not apply missed dose, go back to regular schedule.

Diprolene Side Effects

Overdose symptoms:

Cushing’s syndrome (moon face, weight gain, high blood pressure, emotional disturbances, growth of facial hair in women), high blood sugar, sugar in the urine. Cushing’s syndrome may lead to diabetes mellitus and could become serious. If you suspect an overdose, immediately seek medical attention.

More common side effects: stinging or burning where medication is applied to the skin.

Other Diprolene side effects: acne-like eruptions, atrophy, broken capillaries, cracking or tightening, dryness, infected hair follicles, irritation, itching, prickly heat, rash, redness, sensitivity.


No drug interactions reported with Diprolene.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Diprolene appears in breast milk.

No special precautions apply to seniors.

Not generally prescribed for children under 12 years.

  • Do not use if sensitive to or allergic to Diprolene.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Diprolene side effects, please contact your healthcare provider.