Erythromycin, Topical

Brand names: Akne-Mycin, A/T/S, Erycette, Erygel, T-STAT.

Erythromycin topical is a macrolide antibiotic. It is used to treat a variety of bacterial infections.

Quick Facts About Erythromycin Topical


Used to treat acne.

Erythromycin Topical Dosage

Use exactly as prescribed. Wash affected area with soap and water before applying medication, and wash hands after application.

  • Usual adult dose: A/T/S topical solution — apply 2 times per day to affected area, morning and night. A/T/S topical gel — apply thin film to affected area. Erycette topical solution — rub pledget (pad) over affected area 2 times per day. T-STAT topical solution — apply solution or pads over affected areas 2 times per day.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: apply as soon as possible, unless almost time for next dose. If so, skip missed dose; go back to regular schedule.

Erythromycin Topical Side Effects

Overdose symptoms:

is unlikely; however, not recommended to use in excess. If you suspect an overdose, immediately seek medical attention.

More common side effects: burning sensation, dryness, hives, irritation of eyes, itching, oiliness, peeling, scaling, tenderness, unusual redness of the skin.

No known less common or rare Erythromycin Topical side effects.


Inform your doctor before combining Erythromycin Topical with other topical acne medications.

No known food/other substance interactions.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Should not use if sensitive to or allergic to this medication.
  • May cause new infections that need to be treated with a different antibiotic.
  • If you use other topical acne medications, may experience irritation.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Erythromycin Topical side effects, please contact your healthcare provider.