Generic name: Ofloxacin.

Floxin is a fluoraquinolone antibiotic. It inhibits the growth of bacteria by chemically interfering with their ability to survive. 

Quick Facts About Floxin


Used to treat lower respiratory tract infections, sexually transmitted diseases, pelvic inflammatory disease, and infections of the urinary tract, prostate gland, and skin. Not effective in treating syphilis, and may hide or delay symptoms.

Floxin Dosage

Take exactly as prescribed, finishing the entire prescription. Drink lots of fluids during Floxin therapy.

  • Usual adult dose: for lower respiratory tract infections — Worsening of chronic bronchitis — 400 milligrams every 12 hours for 10 days, up to 800 milligrams per day. Pneumonia — 400 milligrams every 12 hours for 10 days, up to 800 milligrams per day. For sexually transmitted diseases — Gonorrhea — 400 milligrams taken once. Infections of the cervix or urethra — 300 milligrams every 12 hours for 7 days, up to 600 milligrams per day. For mild to moderate skin infections — 400 milligrams every 12 hours for 10 days, up to 800 milligrams per day. For urinary tract infections — Bladder infections — 200 milligrams every 12 hours, totaling 400 milligrams per day. Taken 3 days for coli or K. pneumonia; taken 7 days for other microbes. Complicated urinary tract infections — 200 milligrams every 12 hours for 10 days, totaling 400 milligrams per day. Prostatitis — 300 milligrams every 12 hours for 6 weeks, totaling 600 milligrams per day. Now also comes in solution/drops.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose, go back to regular schedule. Do not double doses.

Floxin Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: diarrhea, difficulty sleeping, dizziness, headache, itching of genital area in women, nausea, vaginal inflammation, vomiting.

Less common Floxin side effects: abdominal pain and cramps, aggressiveness or hostility, agitation, anemia, anxiety, asthma, blood in urine, blurred vision, body pain, bruising, burning or rash of the female genitals, burning sensation in the upper chest, changeable emotions, changes in thinking and perception, chest pain, confusion, conjunctivitis (pink eye), continual runny nose, constipation, cough, decreased appetite, depression, difficult or labored breathing, disorientation, disturbed dreams, disturbed sense of smell, double vision, dry mouth, exaggerated sense of well-being, excessive perspiration, fainting, fatigue, fear, fever, fluid retention, frequent urination, gas, hallucinations, hearing disturbance or loss, hepatitis, hiccups, high or low blood pressure, high or low blood sugar, hives, inability to urinate, increased urination, indigestion, inflammation of the colon, inflammation or rupture of tendons, intolerance to light, involuntary eye movement, itching, joint pain, kidney problems, lack of coordination, light-headedness, liver problems, menstrual changes, muscle pain, nervousness, nightmares, nosebleed, pain, pain in arms and legs, painful or difficult urination, purple or red spots on the skin, rapid heartbeat, rash, reddened skin, restlessness, ringing in the ears, seizures, sensitivity to light, severe allergic reaction, skin inflammation and flaking or eruptions, sleepiness, sleep problems, sore mouth or throat, Stevens-Johnson syndrome, stomach and intestinal upset or bleeding, taste distortion, thirst, throbbing or fluttering heartbeat, tingling or pins and needles, tremor, unexplained bleeding from the uterus, vaginal discharge, vaginal yeast infection, vague feeling of illness, vertigo, visual disturbances, weakness, weight loss, yellowing of eyes and skin.


Inform your doctor before combining Floxin with:

antacids containing aluminum, magnesium, or calcium; blood thinners such as Coumadin; calcium supplements such as Caltrate; cyclosporine (Sandimmune); insulin; iron supplements such as Feosol; multivitamins with zinc; nonsteroidal anti-inflammatory medications such as Motrin and Naprosyn; oral diabetes medications such as Diabinese and Micronase; sucralfate (Carafate); theophylline (Theo-Dur).

Do not take with food. Do not take mineral supplements, vitamins with iron or minerals, or antacids with calcium, aluminum, or magnesium within 2 hours of taking this medication.

Special Cautions

Should not use during pregnancy. If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not take if sensitive to or allergic to this or other quinolone antibiotics such as Cipro and Noroxin.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Immediately stop taking Floxin and contact your doctor if you develop a skin rash or other allergic reaction. In rare cases, serious and fatal allergic reactions occur after the first dose. Signs of allergic reaction: swelling of the face and throat, shortness of breath, difficulty swallowing, rapid heartbeat, tingling, itching and hives.
  • Stop taking Floxin if you experience: convulsions, increased pressure in the head, psychosis, tremors, restlessness, light-headedness, nervousness, confusion, depression, nightmares, insomnia, or hallucinations.
  • Inform your doctor and use with caution if you have: brain disorder, epilepsy, or seizures due to kidney disease.
  • To prevent sun poisoning, avoid long exposure to the sun.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Floxin side effects, please contact your healthcare provider.