Generic name: Gyne-Lotrimin.

Other brand names: Femcare, Lotrimin, Mycelex.

Gyne-Lotrimin is an antifungal. It destroys and prevents the growth of fungi. 

Quick Facts About Gyne-Lotrimin


Used to treat fungal infections.

Gyne-Lotrimin Dosage

Avoid getting into eyes. If taking lozenges, let dissolve in your mouth; do not swallow or chew. To avoid reinfection, use condoms during sexual intercourse. Do not use tampons if using vaginal medication; will absorb medication. Do not douche unless specifically instructed by your doctor.

  • Usual adult dose: Lotrimin — wash hands before and after use. Apply morning and evening to affected areas; massage into skin. Gyne-Lotrimin cream — insert 1 applicatorful vaginally at bedtime for 7 consecutive days. Mycelex troche — 1 troche slowly dissolved orally 5 times per day for 14 consecutive days. For prevention of recurrence, 1 troche 3 times per day.
  • Usual child dose: Lotrimin — wash hands before and after use. Apply morning and evening to affected areas; massage into skin.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule.

Gyne-Lotrimin Side Effects

Overdose symptoms:

no specific information available; overdose unlikely. However, if you suspect an overdose, immediately seek medical attention.

More common side effects: blistering, burning, hives, irritated skin, itching, peeling, reddened skin, stinging, swelling due to fluid retention. Side effects of vaginal preparation: abdominal/stomach cramps and pain, burning and irritation of penis of sexual partner, headache, pain during sexual intercourse, skin rash or hives, vaginal burning and/or itching, soreness during sexual intercourse, unpleasant mouth sensation.

No known less common or rare Gyne-Lotrimin side effects.


No Gyne-Lotrimin drug interactions reported.

No known food/other substance interactions. 

Special Cautions

Do not use during pregnancy without specific instructions from your doctor. Not known whether Gyne-Lotrimin appears in breast milk.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children.

  • If allergic to this medication, should not use.
  • Notify your doctor if you experience increased skin irritations such as redness, itching, burning, blistering, swelling, or oozing.
  • If symptoms do not subside after 2 to 4 weeks, contact your doctor.
  • If you experience abdominal pain, bad-smelling vaginal discharge, or fever, notify your doctor immediately.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Gyne-Lotrimin side effects, please contact your healthcare provider.