Generic name: Hydrochlorothiazide

Other brand names: Aquazide-H, Diaqua, Esidrix, Ezide, Hydro-Chlor, Hyaro-D, Hydromal, Hydro-Par, Hydro-T, Mictrin, Oretic.

HydroDIURIL is a thiazide diuretic. It reduces fluid accumulation in the body.

Quick Facts About HydroDIURIL


Used to treat high blood pressure and conditions requiring elimination of excess body fluid.

HydroDIURIL Dosage

Take exactly as prescribed. May take weeks to observe results; must continue to take even if you feel better.

  • Usual adult dose: for water retention — 25 to 100 milligrams per day as a single dose or divided into smaller doses. Doctor may suggest day on/day off therapy. For high blood pressure — 25 milligrams per day as a single dose, up to 50 milligrams as a single dose or divided into 2 doses.
  • Usual child dose:  1 milligram per 1 pound of body weight divided into 2 doses per day, up to 50 milligrams per day. Under 2 years — Infants under 6 months may be prescribed 1.5 milligrams per 1 pound of body weight per day divided into 2 doses, up to 12.5 to 37.5 milligrams per day maximum. 2 to 12 years — maximum of 37.5 to 100 milligrams per day divided into 2 doses.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose, go back to regular schedule. Do not double doses.

HydroDIURIL Side Effects

Overdose symptoms:

dry mouth, electrolyte imbalance, excessive thirst, muscle pain or cramps, symptoms of low potassium such as dehydration, weak or irregular heartbeat. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal cramping, diarrhea, dizziness when standing up, headache, loss of appetite, low blood pressure, low potassium, stomach irritation or upset, weakness.

Less common or rare side HydroDIURIL side effects: anemia, blood disorders, changes in blood sugar, constipation, difficulty breathing, dizziness, fever, fluid in lungs, hair loss, high levels of sugar in the urine, hives, hypersensitivity reactions, impotence, inflammation of the lung, inflammation of the pancreas, inflammation of the salivary glands, kidney failure, muscle spasms, nausea, rash, reddish or purplish skin spots, skin disorders such as Stevens-Johnson (severe mouth and eye blisters), skin peeling, tingling or pins and needles, vertigo, vision changes, vomiting, yellow eyes and skin.


Inform your doctor before combining HydroDIURIL with:

barbiturates such as phenobarbital; cholestyramine (Questran); colestipol (Colestid); corticosteroids such as Prednisone and adrenocorticotropic hormone (acth); diabetes medications such as insulin and Micronase; lithium; narcotics such as Percocet; nonsteroidal anti-inflammatory medications such as Naprosyn; norepinephrine (Levophed); other high blood pressure medications; skeletal muscle relaxants such as Tubocurarine.

Alcohol may increase sedative effects; do not drink alcohol when taking this medication.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children.

  • If you can’t urinate, you should not take HydroDIURIL.
  • Should not take if sensitive to or allergic to this or similar medications, or sulfa/sulfonamide-derived medications. May be at higher risk for allergy if you have a history of allergies or bronchial asthma.
  • May cause potassium loss; doctor may advise adding foods rich in potassium to your diet or a potassium supplement.
  • Doctor should assess and monitor kidney function during HydroDIURIL therapy.
  • Use with caution if you have: diabetes, gout, liver disease, or lupus erythematosus.
  • If exercising and if in hot weather, use caution not to deplete body fluids; may result in low blood pressure.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or HydroDIURIL side effects, please contact your healthcare provider.