Generic name: Chlorthalidone.

Other brand names: Thalitone.

Hygroton is a thiazide diuretic. It reduces fluid accumulation in the body. 

Quick Facts About Hygroton


Used to treat high blood pressure and conditions requiring elimination of excess body fluid.

Hygroton Dosage

Take exactly as prescribed, with or without food. May take weeks to observe results; you must continue to take even if you feel better. Take in the morning, as it stimulates urination.

  • Usual adult dose: for high blood pressure (Hygroton) — 25 milligrams in a single dose; may be increased by doctor up to 100 milligrams once per day. For high blood pressure (Thalitone) — 15 milligrams in a single dose; may be increased by doctor up to 45 to 50 milligrams once per day. For fluid retention (Hygroton) — 50 to 100 milligrams per day or 100 milligrams every other day, up to 150 to 200 milligrams. For fluid retention (Thalitone) — 30 to 60 milligrams per day or 60 milligrams every other day, up to 90 to 120 milligrams.
  • Usual child dose: not generally recommended for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Hygroton Side Effects

Overdose symptoms:

confusion, dizziness, nausea, weakness. If you suspect an overdose, immediately seek medical attention.

More common side effects: allergic reaction, anemia, changes in blood sugar, change in potassium levels, constipation, cramping, diarrhea, dizziness, dizziness when standing, flaky skin, headache, hives, impotence, inflammation of the pancreas, itching, loss of appetite, low blood pressure, muscle spasms, nausea, rash, restlessness, sensitivity to light, stomach irritation, tingling or pins and needles, vision changes, vomiting, weakness, yellow eyes and skin.

No known less common or rare Hygroton side effects.


Inform your doctor before combining Hygroton with:

appetite-control medications such as Tenuate; colestyramine (Questran); colestipol (Colestid); decongestants; digitalis (Lanoxin); insulin; lithium (Lithonate); oral diabetes medications such as Micronase; other high blood pressure medications such as Catapres and Aldomet; steroids such as prednisone.

Do not drink alcohol while taling Hygroton; increases the risk of dizziness.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally recommended for children.

  • Do not substitute with a generic brand unless specifically directed by your doctor.
  • If you cannot urinate, should not take Hygroton.
  • Should not take if sensitive to or allergic to this or similar medications. Inform your doctor if you have kidney or liver disease, gout, or lupus. May be at higher risk for allergy if you have a history of bronchial asthma.
  • May cause potassium loss; doctor may advise adding foods rich in potassium to your diet or a potassium supplement.
  • Use caution to avoid dehydration in hot weather. If you experience the following, contact your doctor: excessive thirst, increased heart rate or pulse, muscle pains/cramps, nausea, restlessness, tiredness, or vomiting. Also, avoid long sunlight exposure.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Hygroton side effects, please contact your healthcare provider.