Generic name: Loperamide hydrochloride

Other brand names: Imodium A-D, Kaopectate II, Maalox Anti-Diarrheal, Pepto Diarrheal Control.

Imodium is an antidiarrheal. It decreases the passing of water and other substances into the bowel and slows intestinal tract movement. 

Quick Facts About Imodium


Used to treat diarrhea associated with inflammatory bowel disease, not diarrhea caused by a specific germ. Also used to reduce discharge from an ileostomy. May also be used to treat traveler’s diarrhea.

Imodium Dosage

Do not take more than prescribed. Drink plenty of fluids to avoid dehydration while you have diarrhea.

  • Usual adult dose: for severe diarrhea — 2 capsules (4 milligrams), then 1 capsule (2 milligrams) after each loose stool, up to 8 capsules (16 milligrams) per day. Should see improvement within 48 hours. For long-lasting or frequently recurring diarrhea — 2 capsules (4 milligrams), then 1 capsule (2 milligrams) after each loose stool until diarrhea is under control. Dosage then adjusted to meet individual needs. Average maintenance dose is 2 to 4 capsules per day, up to 8 capsules. Contact your doctor if no improvement after 10 days.
  • Usual child dose: for children 2 to 5 years or 44 pounds or less — use nonprescription Imodium A-D liquid. For children 6 to 12 years — use capsules (2 milligrams each) or liquid (1 milligram per teaspoon). Dosage schedule: children 2 to 5 (28-44 pounds) — 1 milligram (1 teaspoonful of liquid) taken 3 times per day. Children 6 to 8 (45-66 pounds) — 2 milligrams taken 2 times per day. Children 8 to 12 years (67 pounds and over) — 2 milligrams taken 3 times per day. Not generally prescribed for children under 2 years.
  • Missed dose: if taking on a regular schedule — take as soon as possible, then take remaining doses at evenly spaced intervals. Skip dose if you do not have diarrhea.

Imodium Side Effects

Overdose symptoms:

constipation, depression, drowsiness, lethargy, nausea. If you suspect an overdose, immediately seek medical attention.

Side effects: abdominal distention, abdominal pain or discomfort, allergic reactions including skin rash, constipation, dizziness, drowsiness, dry mouth, nausea and vomiting, tiredness.

No known less common or rare Imodium side effects.


No reported Imodium drug interactions.

No known food/other substance interactions.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Imodium appears in breast milk.

No special precautions apply to seniors.

Not generally prescribed for children under 2 years. Follow doctor’s instructions carefully for children 2 to 12 years. Use caution administering to young children; unpredictable responses may occur.

  • Do not take if your body cannot tolerate being constipated.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Immediately contact your doctor if diarrhea continues beyond a few days, fever develops, or you observe blood in your stools.
  • If sensitive or allergic to this medication, should not take.
  • Not to be used for acute dysentery (caused by bacteria, viruses, or parasites).
  • Doctor should monitor for central nervous system reactions (drowsiness, convulsions) in the case of liver disease.
  • Discontinue use of Imodium and contact your doctor if you experience abdominal distention, colitis, or intestinal blockage.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Imodium side effects, please contact your healthcare provider.