Generic name: Inderal (propranolol hydrochloride) with hydrochlorothiazide.

Other brand names: Inderide LA.

Inderide is a thiazide diuretic and beta-blocker combination. It slows the heart rate and eliminates urine, thereby reducing high blood pressure.

Quick Facts About Inderide


Used to treat high blood pressure.

Inderide Dosage

Take exactly as prescribed. If you miss doses, may 1 worsen condition. Best if taken before meals. May take weeks to observe results if taking for high blood pressure; must continue to take even if you begin to feel better. Do not stop medication suddenly; gradually taper.

  • Usual adult dose: 1 tablet taken 2 times per day.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless within 8 hours of next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Inderide Side Effects

Overdose symptoms:

coma, extremely slow heartbeat, heart failure, increased urination, irritation and overactivity of stomach and intestines, low blood pressure, sluggishness, stupor, wheezing. If you suspect an overdose, immediately seek medical attention.

More common side effects: allergic reactions (fever, rash, aching and sore throat), anemia, blood disorders, blurred vision, constipation, congestive heart failure, cramps, decreased mental clarity, depression, diarrhea, difficulty breathing, difficulty sleeping, disorientation, dizziness, dizziness upon standing, dry eyes, emotional changeability, exhaustion, fatigue, hair loss, hallucinations, headache, high blood sugar, hives, increased skin sensitivity to sunlight, inflammation of the large intestine or the pancreas, inflammation of the salivary glands, light-headedness, loss of appetite, low blood pressure, lupus erythematosus, male impotence, muscle spasms, nausea, restlessness, shortterm memory loss, slow heartbeat, stomach irritation, sugar in urine, tingling or pins and needles, upset stomach, vertigo, visual disturbances, vivid dreams, vomiting, weakness, wheezing, yellow eyes and skin.

No known less common or rare Inderide side effects.


Inform your doctor before combining Inderide with:

ACTH (adrenocorticotropic hormone); aluminum hydroxide gel (Mylanta); calcium blockers such as Calan, Cardizem, and Procardia XL; certain blood pressure medications such as Diupres and Ser-Ap-Es; chlorpromazine (Thorazine); corticosteroids such as prednisone; digitalis (Lanoxin); epinephrine (EpiPen); haloperidol (Haldol); insulin; lidocaine (Xylocaine); nonsteroidal anti-inflammatory medications such as Motrin; norepinephrine (Levophed); oral diabetes medications such as Micronase; phenobarbital; phenytoin (Dilantin); rifampin (Rifadin); theophylline (Theo-Dur); thyroid medications such as Synthroid.

Avoid alcohol while taking Inderide. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not take if unable to urinate or sensitive to or allergic to this medication or sulfa medications.
  • Should not take or should use with extreme caution if you have: bronchial asthma, certain types of irregular heartbeat, inadequate blood supply to the circulatory system, kidney or liver disease, seasonal allergies or other bronchial conditions, severe congestive heart failure, or slow heartbeat. Doctor will decide whether to prescribe depending on your condition.
  • Inform your doctor if you are diabetic; medication may cover the symptoms of low blood sugar or alter blood sugar levels.
  • May interfere with glaucoma screening; eye pressure may increase when Inderide is stopped.
  • Inform your doctor or dentist prior to surgery or dental treatment, or during a medical emergency.
  • May cause potassium loss; if so, doctor will advise you to add potassium-rich foods to your diet or to take a potassium supplement

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Inderide side effects, please contact your healthcare provider.