Generic name: Fluvastatin sodium.

Lescol is an antihyperlipidemic. It interferes with the enzyme that synthesizes cholesterol, thereby decreasing the low-density lipoprotein (LDL) in the blood. 

Quick Facts About Lescol


Used to lower cholesterol levels. Also used to slow the build-up of plaque in coronary arteries.

Lescol Dosage

Take at bedtime, either with or without food. Ad here to diet and exercise program; Lescol supplements these measures.

  • Usual adult dose: 20 milligrams per day taken in one dose at bedtime, up to 40 milligrams per day as a single dose. Doctor may alter initial dosage after 4 weeks. If taking with other cholesterol medications, take the other medications at least 2 hours prior to taking Lescol.
  • Usual child dose: not prescribed for children under 18 years.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose, go back to regular schedule. Do not double doses.

Lescol Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, accidental injury, back pain, diarrhea, fatigue, flu-like symptoms, headache, indigestion, joint disease, muscle pain, nasal inflammation, nausea, sore throat, upper respiratory infection.

Less common Lescol side effects: allergy, bronchitis, constipation, coughing, dizziness, dental problems, gas, inflamed sinuses, insomnia, rash.


Inform your doctor before combining Lescol with:

cholestyramine (Questran); cimetidine (Tagamet); clofibrate (Atromid-S); cyclosporine (Sandimmune); digoxin (Lanoxin); erythromycin (E-Mycin or E.E.S.); gemfibrozil (Lopid); ketoconazole (Nizoral); omeprazole (Prilosec); ranitidine (Zantac); rifampin (Rifadin); spironolactone (Aldactone or Aldactazide).

No known food/other substance interactions.

Special Cautions

Do not take if pregnant or nursing. Lescol lowers cholesterol needed by a developing baby, and it appears in breast milk.

No special precautions apply to seniors.

Not prescribed for children under 18 years.

  • Lescol therapy usually starts after doctor structures a cholesterol-lowering diet.
  • Avoid if you have liver problems or are/have been a heavy drinker.
  • Should not take if sensitive to or allergic to Lescol.
  • Doctor may order test to check liver enzyme levels prior to taking medication; there is some risk for liver damage with Lescol. Monitoring will continue once Lescol therapy begins.
  • Inform your doctor if you experience: unexplained muscle pain, tenderness, weakness, fever, or if you feel sick at the start of taking this medication; may be signs of muscle tissue damage.
  • If factors increasing risk of muscle and/or kidney damage appear, doctor may temporarily discontinue this medication.
  • Inform your doctor of any medical conditions present before starting medication.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Lescol side effects, please contact your healthcare provider.