Generic name: Chlordiazepoxide.

Other brand names: Libritabs, Lipoxide, Mitran.

Librium is a benzodiazepine sedative. It relieves anxiety by depressing the central nervous system. 

Quick Facts About Librium


Used to treat anxiety disorders. Also used to provide short-term relief for symptoms of anxiety, alcohol withdrawal in the case of alcoholism, and apprehension prior to surgery.

Librium Dosage

Take exactly as prescribed. Never increase dose; can be habit-forming and cause dependence. To avoid withdrawal symptoms, gradually taper off when discontinuing, per your doctor’s instructions.

  • Usual adult dose: For mild or moderate anxiety — 5 or 10 milligrams taken 3 or 4 times per day. For severe anxiety — 20 to 25 milligrams taken 3 or 4 times per day. For apprehension prior to surgery — 5 to 10 milligrams taken 3 or 4 times per day for days preceding surgery. For alcohol withdrawal — 50 to 100 milligrams orally, repeated up to a maximum of 300 milligrams per day until anxiety is controlled. Dose then reduced to smallest possible level. Seniors — 5 milligrams taken 2 to 4 times per day.
  • Usual child dose (for children 6 years and older): 5 milligrams taken 2 to 4 times per day. Not recommended for children under 6 years.
  • Missed dose: take as soon as possible, unless within an hour of next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Librium Side Effects

Overdose symptoms:

coma, confusion, slow reflexes, sleepiness. If you suspect an overdose, immediately seek medical attention.

More common side effects: confusion, constipation, drowsiness, feinting, increased or decreased sex drive, liver problems, lack of muscle coordination, minor menstrual irregularities, nausea, skin rash or eruptions, swelling due to fluid retention, yellow eyes and skin. Side effects due to abrupt decrease or withdrawal: abdominal and muscle cramps, convulsions, exaggerated feeling of depression, sleeplessness, sweating, tremors, vomiting.

No known less common or rare Librium side effects.


Inform your doctor before combining Librium with:

antacids such as Maalox and Mylanta, antidepressants such as Nardil and Parnate, barbiturates such as phenobarbital, blood thinners such as Coumadin, cimetidine (Tagamet), disulfiram (Antabuse), levodopa (Laradopa), major tranquilizers such as Stelazine and Thorazine, narcotic pain relievers such as Demerol and Percocet, oral contraceptives.

Do not drink alcohol when taking Librium; may intensify effects of alcohol.

Special Cautions

Do not take Librium if pregnant or planning to become g pregnant Increased risk of birth defects. May appear in breast milk.

Seniors are prescribed reduced doses.

Follow doctor’s instructions carefully for children.

  • May decrease alertness. Notify your doctor if you observe contrary reactions such as excitement, stimulation, or acute rage. Not prescribed for children under 6 years.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Inform your doctor before starting Librium if you are severely depressed or have a history of severe depression, or if you have porphyria or liver or kidney disease.
  • If sensitive to or allergic to this or similar tranquilizers, should not take.
  • Librium is not to be used for everyday stress, tension, or anxiety.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Librium side effects, please contact your healthcare provider.