Generic name: Gemfibrozil.

Lopid is an antihyperlipidemic (lipid-lowering medication). It is thought to work by reducing the body’s production of certain fats.

Quick Facts About Lopid


Used to treat high levels of fatty substances in the blood in people at risk for inflammation of the pancreas, who do not respond to a strict diet. Is prescribed along with a special diet. Also used to reduce risk of coronary heart disease where diet, exercise, and other medications have failed.

Lopid Dosage

Take exactly as prescribed. Strictly adhere to diet and exercise plan developed by your doctor.

  • Usual adult dose: 1,200 milligrams divided into 2 doses — 30 minutes before morning and evening meals. Seniors — use with caution.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: if within 4 hours of next dose, do not take missed dose; go back to regular schedule. Do not double doses.

Lopid Side Effects

Overdose symptoms:

no reported cases of overdose. However, if you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, acute appendicitis, constipation, diarrhea, eczema, fatigue, headache, indigestion, nausea/vomiting, rash, vertigo.

Less common or rare Lopid side effects: anemia, blood disorders, blurred vision, confusion, convulsions, decreased male fertility, decreased sex drive, depression, dizziness, fainting, hives, impotence, inflammation of colon, irregular heartbeat, itching, joint pain, laryngeal swelling, muscle disease, muscle pain, muscle weakness, painful extremities, sleepiness, tingling sensation, weight loss, yellow eyes and skin.


Inform your doctor before combining Lopid with:

blood thinners such as Coumadin, colestipol (Colestid), glyburide (Micronase), lovastatin (Mevacor), pravastatin (Pravachol).

Doctor may advise you to stop drinking alcohol during Lopid therapy, as it may lead to high levels of fats in the body.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Seniors should use with caution.

Not generally prescribed for children.

  • Slight risk of developing: malignancy, gallbladder disease, abdominal pain leading to appendectomy, or other serious or fatal abdominal disorders; should not be used if you have mildly elevated cholesterol levels.
  • Do not take if you are taking medication for severe kidney or liver disorders or gallbladder disease, unless directed by your doctor.
  • Inform your doctor before Lopid therapy if you are being treated for diseases that increase blood cholesterol, including: overactive thyroid, diabetes, kidney and blood vessel disorder, excess protein in the blood, or obstructive liver disease.
  • Lopid is a supplement to other weight loss measures, not a substitute.
  • If sensitive to or allergic to this or similar medications, should not take.
  • Doctor may advise you to lose weight before starting Lopid therapy as excess weight may lead to unusually high levels of fats in the body.
  • Doctor should monitor blood levels during first year of Lopid therapy due to risk of blood diseases. Will also periodically test your liver function due to risk of liver disorders with Lopid.
  • If cholesterol is not lowered in first 3 months of Lopid therapy, doctor will discontinue medication.
  • May increase risk for myositis, muscle inflammation. Inform your doctor if you experience muscle pain, tenderness, or weakness.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Lopid side effects, please contact your healthcare provider