Generic name: Benazepril hydrochloride.

Lotensin is an angiotensin-converting enzyme (ACE) inhibitor. It works to reduce blood pressure by preventing angiotensin I from converting into a more potent enzyme that increases salt and water retention. 

Quick Facts About Lotensin


Used to treat high blood pressure.

Lotensin Dosage

Take with or without food; do not use salt substitutes that contain potassium. Adhere to prescription schedule; abrupt discontinuance can increase blood pressure. Must take regularly for Lotensin to be effective.

  • Usual adult dose: If not using a diuretic — 10 milligrams one time per day, initially. Ongoing dose — 20 to 40 milligrams per day taken in a single dose or divided into 2 equal doses, up to 80 milligrams per day maximum. If using a diuretic — 5 milligrams per day. If patient can tolerate not taking diuretic, should be stopped 2 to 3 days before starting Lotensin therapy. For reduced kidney function — 5 milligrams per day, up to 40 milligrams per day maximum. If using kidney dialysis, doctor may prescribe a different medication. Seniors — should use with caution.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Lotensin Side Effects

Overdose symptoms:

sudden drop in blood pressure, If you suspect an overdose, immediately seek medical attention.

More common side effects: cough, dizziness, fatigue, headache, high potassium levels, nausea. Immediately contact your doctor if you experience: swelling of the face around the lips, tongue, or throat; swelling of arms and legs; sore throat; fever and chills; or difficulty swallowing; may be an emergency situation.

Less common or rare Lotensin side effects: allergic reactions; anxiety; arthritis; asthma; bronchitis; chest pain; constipation; dark tarry stool with blood; decreased sex drive; difficulty sleeping; dizziness upon standing; fainting; fluid retention; flushing; impotence; infection; inflammation of the skin; inflammation of the stomach; itching; joint pain; low blood pressure; muscle pain; nervousness; pounding heartbeat; rash; sensitivity to light; shortness of breath; sinus inflammation; sweating; swelling of arms, legs, face; tingling or pins and needles; urinary infection; vomiting; weakness.


Inform your doctor before combining Lotensin with:

diuretics such as Dyazide and Lasix, lithium (Lithonate), potassium supplements such as Slow-K, potassium-sparing diuretics such as Moduretic.

No known food/other substance interactions. 

Special Cautions

If taken during 2nd and 3rd trimesters can cause death to developing babies and newborns. If pregnant or planning to become pregnant, inform your doctor immediately. Small amounts appear in breast milk; could affect a nursing infant.

Seniors should use with caution.

Not generally prescribed for children.

  • Do not take if sensitive to or allergic to this or other ACE inhibitors.
  • Immediately contact your doctor if you experience sore throat or fever.
  • Doctor should assess kidney function prior to and during Lotensin therapy; may prescribe different medication if you are on kidney dialysis.
  • If you feel light-headed or faint in first few days, may be due to low blood pressure.
  • Immediately contact your doctor.
  • Use with caution if you have congestive heart failure.
  • Be aware that excessive sweating, dehydration, severe diarrhea, or vomiting can deplete your body’s fluids and cause low blood pressure.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Lotensin side effects, please contact your healthcare provider.