Generic name: Indapamide.

Lozol is a thiazide diuretic. It promotes the loss of salt and water in the body, and increases the diameter of the blood vessels, thereby lowering blood pressure. 

Quick Facts About Lozol


Used to treat high blood pressure. Also used to reduce salt and fluid retention. May be prescribed to reduce fluid retention in pregnant women.

Lozol Dosage

Take exactly as prescribed. Never stop this medication abruptly; may cause condition to worsen. Must take regularly for Lozol to be effective; may take several weeks before you observe full effects. Continue to take even if you feel well.

  • Usual adult dose: for high blood pressure — 1.25 milligrams as a single dose taken in the morning. Doctor may increase gradually up to 5 milligrams per day if initial dose is ineffective. For fluid buildup in congestive heart failure — 2.5 milligrams as a single daily dose taken in the morning. Doctor may increase gradually up to 5 milligrams per day if initial dose is ineffective.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Lozol Side Effects

Overdose symptoms:

electrolyte imbalance, nausea, stomach disorders, vomiting, weakness. If you suspect an overdose, immediately seek medical attention.

More common side effects: agitation, anxiety, back pain, dizziness, headache, infection, irritability, muscle cramps or spasms, nasal inflammation, nervousness, numbness in hands and feet, pain, tension, weakness, fatigue, loss of energy or tiredness.

Less common or rare Lozol side effects: abdominal pain or cramps, blurred vision, chest pain, conjunctivitis, constipation, cough, depression, diarrhea, dizziness when standing up quickly, drowsiness, dry mouth, excessive urination at night, fluid retention, flu-like symptoms, flushing, fluttering heartbeat, frequent urination, hives, impotence or reduced sex drive, indigestion, insomnia, irregular heartbeat, itching, light-headedness, loss of appetite, nausea, nervousness, premature heart contractions, production of large amounts of pale urine, rash, runny nose, sore throat, stomach irritation, tingling in hands and feet, vertigo, vomiting, weakness, weak or irregular heartbeat, weight loss.


Inform your doctor before combining Lozol with:

lithium (Eskalith), norepinephrine, other high blood pressure medications such as Aldomet and Tenormin. Taking Lozol with lithium increases the risk of lithium poisoning.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Senior women are particularly susceptible to salt and potassium loss. Doctor may advise potassium-rich diet or potassium supplement.

Not generally prescribed for children.

  • Should not use if you are unable to urinate; have an allergic reaction to Lozol; or are sensitive to other sulfa-containing medications.
  • Risk of potassium loss increases as dose is increased if you have cirrhosis, are using corticosteroids or adrenocorticotropic hormone (acth).
  • Doctor should regularly do blood tests if you have irregular heartbeat or are taking heart medications.
  • Use with caution if you have: gout or high uric acid levels, liver disease, diabetes, lupus erythematosus, or kidney disease. Doctor should do kidney assessment and continual monitoring.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Lozol side effects, please contact your healthcare provider.