Generic name: Trandolapril.

Mavik is known as an angiotensin-converting enzyme (ACE) inhibitor. It prevents angiotensin I, a blood chemical, from developing into angiotensin II, a stronger form that increases salt and water levels in the body. It also expands blood vessels in the body, further reducing blood pressure. 

Quick Facts About Mavik


Used to treat high blood pressure. Effective used alone or in conjunction with other high blood pressure medications such as diuretics. Does not cure high blood pressure; merely keeps it under control.

Mavik Dosage

Take with or without meals as directed by your doctor at the same time every day. Must take regularly for Mavik to be effective. Do not stop drug without consulting doctor.

  • Usual adult dose: initially — 1 milligram once per day. For African-Americans, initially—2 milligrams once per day. For both the above — doctor may increase dosage at 1-week intervals, up to 2 to 4 milligrams once per day. Doctor may increase dosage further to 4 milligrams twice per day to be taken in combination with a diuretic. For patients already taking a diuretic — doctor will have you stop taking it 2 to 3 days before treatment with Mavik or prescribe an initial dosage of 0.5 milligrams once per day. For patients with liver or kidney disease, initially — 0.5 milligrams once per day.
  • Usual child dose: Not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not take double doses.

Mavik Side Effects

Overdose symptoms:

severe drop in blood pressure. If you suspect an overdose, immediately seek medical attention.

More common side effects: dizziness, fatigue, headache, nausea, temporary chronic cough.

Less common Mavik side effects: abdominal pain, breathing difficulties, bronchitis, chest tightness or pain, diarrhea, dizziness when rising from a sitting or lying position, fainting, nausea, rash, urinary tract infection, vomiting, weakness. Rare side effects: abnormal heart rhythm, anxiety, appetite changes, arthritis, asthma, blood in stool, depression, difficulty sleeping, fever, flushing, general feeling of ill health, hair loss, heart attack, heart palpitations, hepatitis and jaundice, impotence, inflammation of pancreas, itching, muscle aches, muscle cramps or weakness, nervousness, reduced sex drive, respiratory infections, sinus irritation, stroke, sweating, swelling of arms, legs, lips, tongue, face, and throat, taste changes, tingling in hands and feet, unusual sensitivity to sun, upset stomach.


Inform your doctor before combining Mavik with:

diuretics such as HydroDIURIL; diuretics that spare the body’s potassium such as Aldactone, Dyazide, and Moduretic; Lithium (Lithonate); potassium supplements such as Micro-K and Slow-K; salt substitutes containing potassium.

Take Mavik with food if it causes upset stomach. 

Special Cautions

Mavik can cause injury and death to a fetus when used during the second and third trimesters. If pregnant or planning to become pregnant, stop taking medication and inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Seniors may be prescribed a lower dose due to age-related losses in kidney or liver functions.

Not generally prescribed for children.

  • If swelling of the face, lips, tongue, throat, arms, or legs, or difficulty breathing occurs, contact your doctor immediately; this may be an emergency situation.
  • Your kidney function should be thoroughly assessed before beginning medication and monitored regularly throughout therapy. Kidney dialysis increases danger of allergic reaction to Mavik.
  • Should not take medication if allergic to it or similar medications, such as Capoten and Vasotec.
  • Inform your doctor before starting Mavik therapy if you have congestive heart failure.
  • Doctor should monitor you closely when you start and after each dosage increase.
  • Monitor vomiting, diarrhea, and heavy perspiration; dehydration can drop your blood pressure. Avoid strenuous exercise and very hot weather, and drink plenty of water. If combining Mavik with high doses of diuretics, your doctor may reduce your diuretic.
  • May affect the liver. Stop treatment and notify doctor immediately if skin or whites of eyes begin to turn yellow.
  • If sore throat or fever occurs, contact your doctor immediately.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Mavik side effects, please contact your healthcare provider.