Generic name: Lomefloxacin hydrochloride.

Maxaquin is a fluoroquinolone antibiotic. It inhibits the growth of bacteria by chemically interfering with their ability to survive. 

Quick Facts About Maxaquin


Used to treat lower respiratory infections including bronchitis, and urinary tract infections. Also used prior to bladder surgery to prevent infection.

Maxaquin Dosage

Finish entire medication, otherwise symptoms may return. May take with or without food; take with a full 8-ounce glass of water. Drink lots of liquids during Maxaquin therapy.

  • Usual adult dose:  for chronic bronchitis — 400 milligrams once per day for 10 days. For cystitis — 400 milligrams once per day for 10 days. For urinary tract infections — 400 milligrams once per day for 14 days. For impaired renal function or cirrhosis — doctor will adjust dose. For dialysis patients — 400 milligrams followed by daily maintenance doses of 200 milligrams taken once per day.
  • Usual child dose: not generally prescribed for children under 18 years.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Maxaquin Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: headache, nausea.

Less common Maxaquin side effects: diarrhea, dizziness, sensitivity to light. Rare side effects: abdominal pain, abnormal or terrifying dreams, abnormal vision, agitation, allergic reaction, altered taste, angina pectoris (crushing chest pain), anxiety, back pain, bleeding between menstrual periods, bleeding in stomach and intestines, blood clots in the lungs, blood in the urine, blue skin color, chest pain, chills, coma, confusion, conjunctivitis (pink eye), constipation, convulsions, cough, decreased heat tolerance, depression, difficult or labored breathing, difficulty swallowing, dry mouth, earache, eye pain, facial swelling, fainting, fatigue, fluid retention and swelling, flu-like symptoms, flushing, gas, general feeling of illness, gout, heart attack, heart failure, high blood pressure, hives, inability to sleep, increased appetite, increased mucus from the lungs, increased sweating, indigestion, inflammation in male genital area, inflammation of stomach and intestines, inflammation of vagina, irregular heartbeat, itching, joint pain, lack of urine, leg cramps, loss of appetite, loss of sense of identity, low blood pressure, low blood sugar, lung infection or other problems, muscle pain, nervousness, nosebleed, overactivity, pain in the genital-rectal area, problems with urination, purple or red skin spots, rapid heartbeat, rash, ringing in ears, skin disorders, skin eruptions or peeling, sleepiness, slow heartbeat, thirst, tingling or pins and needles, tongue discoloration, tremor, vaginal yeast infection, vertigo, vomiting, weakness, wheezing, white or yellow vaginal discharge.


Inform your doctor before combining Maxaquin with:

antacids containing magnesium or aluminum such as Maalox and Turns, caffeine, cimetidine (Tagamet), cydosporine (Sandimmune), probenecid (Benemid), sucralfate (Carafate), theophylline (Theo-Dur), warfarin (Coumadin), vitamins or products containing iron or zinc.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Maxaquin appears in breast milk.

No special precautions apply to seniors.

Not generally prescribed for children under 18 years.

  • Severe or fatal reactions have on rare occasion been experienced after one dose.
  • Immediately seek medical help if you experience: confusion, convulsions, difficulty breathing, hallucinations, hives, itching, light-headedness, loss of consciousness, rash, restlessness, swelling in the face or throat, tingling, or trembling.
  • Can cause mild to life-threatening bowel inflammation. Inform your doctor if you have experienced diarrhea from other antibiotics.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • May cause sensitivity if exposed to sunlight or sunlamps even if sunblock is used. Should avoid exposure even to indirect sunlight during and for several days after therapy is completed.
  • If sensitive to or allergic to this or similar medications, should not take.
  • Use cautiously if you have: epilepsy, hardening of brain arteries, or other conditions that cause seizures.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Maxaquin side effects, please contact your healthcare provider.