Generic name: Methylergonovine maleate.

Methergine is an oxytocic, a blood-vessel constrictor. It increases uterine contractions that impede uterine blood flow. 

Quick Facts About Methergine


Used to control or prevent excessive bleeding after childbirth.

Methergine Dosage

Take exactly as prescribed.

  • Usual adult dose: 0.2 milligram tablet 3 or 4 times per day for up to 1 week.
  • Usual child dose: not prescribed for children.
  • Missed dose: do not take missed dose; do not double doses; go back to regular schedule.

Methergine Side Effects

Overdose symptoms:

abdominal pain, coma, convulsions, elevated blood pressure, hypothermia (drop in body temperature), lowered blood pressure, nausea, numbness, slowed breathing, tingling of arms and legs, vomiting. If you suspect an overdose, immediately seek medical attention.

More common side effects: high blood pressure, low blood pressure.

Less common or rare Methergine side effects: bad taste, blood clots, blood in urine, chest pains (temporary), diarrhea, difficult or labored breathing, dizziness, edema, hallucinations, leg cramps, nasal congestion, nausea, palpitations, ringing in ears, sweating, vomiting.


Inform your doctor before combining Methergine with:

other blood-vessel constrictors such as EpiPen, other ergot-derived medications such as Ergotrate.

No known food/other substance interactions. 

Special Cautions

Should not take if pregnant. If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not prescribed for children.

  • Inform your doctor of any existing blood-vessel disorders, infections, or liver or kidney problems.
  • Should not take if you have high blood pressure or toxemia (poisons circulating in the blood).

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Methergine side effects, please contact your healthcare provider.