Generic name: Lovastatin.

Mevacor is an antihyperlipidemic (lipid-lowering medication). It is thought to work by reducing the body’s production of certain fats.

Quick Facts About Mevacor


Used to lower cholesterol levels in people with primary hypercholesterolemia. May reduce both low-density lipoprotein (LDL or “bad cholesterol”) and high-density lipoprotein (HDL or “good cholesterol”). Prescribed when diet alone does not sufficiently lower cholesterol levels. Also used to slow the build-up of plaque in coronary arteries.

Mevacor Dosage

Take exactly as prescribed, with meals. To get full benefit of Mevacor, adhere to diet and exercise program.

  • Usual adult dose: 20 milligrams once per day, taken with the evening meal, up to 80 milligrams maximum. If taking with immunosuppressive drugs, 10 milligrams per day is prescribed, up to 20 milligrams per day. Doctor should monitor cholesterol levels.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Mevacor Side Effects

Overdose symptoms:

no reported cases, however, if you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain or cramps, altered sense of taste, blurred vision, constipation, diarrhea, dizziness, gas, headache, heartburn, indigestion, itching, muscle cramps, muscle pain, nausea, rash, weakness. Mevacor side effects are usually mild and last for a short period of time, if they appear.

No known less common or rare Mevacor side effects.


Inform your doctor before combining Mevacor with:

blood thinners such as Coumadin; cyclosporine (Sandimmune) and other immunosuppressive medications; erythromycin (E.E.S. or pce); gemfibrozil (Lopid); nicotine acid or niacin (Nicobid).

No known food/other substance interactions. 

Special Cautions

Do not take if pregnant or nursing; may cause damage to fetus or nursing infant If pregnant or planning to become pregnant, inform your doctor immediately.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not take if being treated for acute muscle disease or liver disease, or if you are at risk for developing kidney failure due to muscle tumors.
  • Inform your doctor before starting Mevacor if you are being treated for any disease that contributes to increased blood cholesterol — hypothyroidism, diabetes, kidney and blood vessel disorder, excess protein in the blood, or liver disease.
  • Doctor should perform liver function tests before treatment; every 6 weeks (for 3 months) after Mevacor therapy begins; every 8 weeks during the rest of the first year; then at 6-month intervals.
  • If sensitive to or allergic to this or similar medications, should not take.
  • Use with caution if you have past history of liver disease or consume large amounts of alcohol.
  • Monitor for signs and symptoms of muscle pain, tenderness, or weakness with fever or general bodily discomfort, especially during the starting months of therapy and whenever dose is increased.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Mevacor side effects, please contact your healthcare provider.