Generic name: Prazosin hydrochloride.

Minipress is an antihypertensive. It is thought to act on the central nervous system to prevent the release of chemicals responsible for maintaining high blood pressure. 

Quick Facts About Minipress


Used to treat high blood pressure. Also used to treat benign prostatic hyperplasia (BPH), enlargement of the prostate gland.

Minipress Dosage

Take with or without food. May take weeks to observe results if taking for high blood pressure; must continue to take even if you feel better. Adhere to schedule; if not taken regularly, blood pressure will increase.

  • Usual adult dose: initial dose — 1 milligram taken 2 or 3 times per day. Regular dose — 6 to 15 milligrams per day divided into smaller doses, up to 40 milligrams maximum.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Minipress Side Effects

Overdose symptoms:

extreme drowsiness, low blood pressure. If you suspect an overdose, immediately seek medical attention.

More common side effects: dizziness, drowsiness, headache, lack of energy, nausea, palpitations, weakness.

Less common Minipress side effects: blurred vision; constipation; depression; diarrhea; dizziness upon standing; dry mouth; fainting; fluid retention; frequent urination; nasal congestion; nervousness; nosebleeds; rash; red eyes; shortness of breath; vertigo; vomiting. Rare side effects: abdominal discomfort or pain; excessive perspiration; fever; hair loss; hallucinations; impotence; inability to hold urine; inflammation of the pancreas; itching; itchy purple spots on wrists, forearms, and thighs; joint pain; persistent, painful erection; rapid heartbeat; ringing in ears; tingling or pins and needles.


Inform your doctor before combining Minipress with:

beta-blockers such as Inderal; dextroamphetamine (Dexedrine); diuretics such as Dyazide; ibuprofen (Motrin or Advil); other high blood pressure medications; verapamil (Calan or Verelan).

Avoid alcohol; may intensify its effects. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • May cause dizziness when first starting medication. Avoid any hazardous activities such as driving for 24 hours after first dose, and after each dose increase. At risk for dizziness in hot weather, during exercise, or standing for long periods.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Minipress side effects, please contact your healthcare provider.