Generic name: Minocycline hydrochloride.

Other brand names: Dynacin.

Minocin is a tetracycline antibiotic. It is used to prevent bacteria from multiplying and growing. It is an alternative drug for those who are allergic to penicillin. 

Quick Facts About Minocin


Used to treat infections, including: acne, amebic dysentery, anthrax (rare skin infection), cholera, gonorrhea, plague, respiratory infections such as pneumonia, Rocky Mountain spotted fever, syphilis, urinary tract infections caused by certain microbes.

Minocin Dosage

Take the entire prescription, even if you feel better after a few days. Adhere to schedule to keep a constant level of the medication in the body. May take with or without food; drink plenty of fluids.

  • Usual adult dose: 200 milligrams followed by 100 milligrams every 12 hours. Doctor may increase dose to two or four 50-milligram capsules followed by one 50-milligram capsule 4 times per day.
  • Usual child dose: for children 8 years and older — 4 milligrams per 2.2 pounds of body weight, followed by 2 milligrams per 2.2 pounds of body weight every 12 hours.
  • Missed dose: take as soon as possible; then take remaining doses at evenly spaced intervals for that day. Never double doses.

Minocin Side Effects

Overdose symptoms:

no specific information available. However, if you suspect an overdose, immediately seek medical attention.

More common side effects: aching or inflamed joints, anal or genital sores with fungus infection, anaphylaxis (life-threatening allergic reaction), anemia, appetite loss, blurry vision, bulging of soft spots on infants’ heads, decreased hearing, diarrhea, difficulty swallowing, discoloration of children’s teeth, fluid retention, headache, hepatitis, hives, inflammation of head of penis, inflammation of intestines, inflammation of tongue, nausea, rash, sensitivity to light, skin coloration, skin inflammation and peeling, throat irritation, vomiting.

No known less common or rare Minocin side effects.


Inform your doctor before combining Minocin with:

blood thinners such as Coumadin, oral contraceptives, penicillin (Pen*Vee K).

Avoid using antacids containing aluminum, calcium, or magnesium, such as Maalox, and iron preparations such as Feosol, or take 2 to 3 hours before or after taking Minocin. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May cause discoloration of baby’s teeth if taken in 2nd half of pregnancy. Minocin may cause other harm to a developing baby, so should take only if it cannot be replaced with a non-tetracycline antibiotic. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children 8 years and older. Not generally prescribed for children under 8 years.

  • Do not take if allergic to tetracycline antibiotics.
  • Should not be used to treat meningococcal meningitis; is used only to kill the meningococcal bacteria in people who are carriers.
  • Not for use in treating a staph infection.
  • If you have a kidney disorder, normal dosage levels will trigger overdose. Doctor should frequently test your blood for overdosage.
  • May cause dizziness when first starting medication. Avoid any hazardous activities such as driving until you know how the medication affects you.
  • Use care in sunlight; may cause sensitivity and easy sunburning. If you experience red and/or hot skin, immediately stop taking Minocin.
  • Contact your doctor immediately if you develop a fungus infection, such as a yeast infection.
  • Monitor for signs of fluid buildup in the skull — adults (headache, blurry vision) and infants (“soft spots”, or fontanels, on the head). Immediately stop taking, contact your doctor.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Minocin side effects, please contact your healthcare provider.