Generic name: Thiothixene.

Navane is an antipsychotic. It calms certain areas of the brain while allowing the rest of the brain to function normally. 

Quick Facts About Navane


Used to treat psychotic disorders.

Navane Dosage

May take in liquid or capsule form. Use dropper supplied with medication if taking liquid form.

  • Usual adult dose: milder conditions — 6 milligrams per day total, divided into 3 equal doses. Doctor may increase up to 15 milligrams per day total. For more severe conditions — 10 milligrams per day total, divided into 2 equal doses. Doctor may prescribe up to 60 milligrams per day total. Seniors — usually prescribed lower doses to avoid low blood pressure.
  • Usual child dose: not generally prescribed for children under 12 years.
  • Missed dose: take as soon as possible, unless within 2 hours of next dose. If so, skip missed dose; go back to regular schedule. Do not double doses.

Navane Side Effects

Overdose symptoms:

central nervous system depression, coma, difficulty swallowing, dizziness, drowsiness, head tilted to the side, low blood pressure, muscle twitching, rigid muscles, salivation, tremors, walking disturbances, weakness. If you suspect an overdose, immediately seek medical attention.

More common side effects: abnormal muscle rigidity, abnormal milk secretion, abnormalities in movements and posture, agitation, anemia, blurred vision, breast development in males, chewing movements, constipation, diarrhea, dizziness, drowsiness, dry mouth, excessive thirst, eyeball rotation or state of fixed gaze, feinting, fatigue, fluid accumulation and swelling, headache, high fever, high or low blood sugar, hives, impotence, insomnia, intestinal blockage, involuntary movements of arms and legs, irregular menstrual periods, itching, light-headedness, loss or increase of appetite, low blood pressure, narrow or dilated pupils of the eye, nasal congestion, nausea, painful muscle spasm, protruding tongue, puckering of mouth, puffing of cheeks, rapid heartbeat, rash, restlessness, salivation, sedation, seizures, sensitivity to light, severe allergic reaction, skin inflammation and peeling, strong reflexes, sweating, swelling of breasts, tremors, twitching (in the body, neck, shoulders, and face), visual problems, vomiting, weakness, weight increase, worsening of psychotic symptoms.

No known less common or rare Navane side effects.


Inform your doctor before combining Navane with:

antihistamines such as Benadryl; barbiturates such as phenobarbital; medications containing atropine such as Donnatal. Painkillers, narcotics, or sleeping medications may cause extreme drowsiness.

Alcohol may cause extreme drowsiness.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known whether Navane appears in breast milk; doctor may have you discontinue breastfeeding during Navane therapy.

Senior women at higher risk for tardive dyskinesia — involuntary muscle spasms and twitches in face and body. Seniors are generally at risk for developing low blood pressure; lower doses are prescribed as a result

Not generally prescribed for children under 12 years.

  • Do not administer to comatose patients.
  • Do not take if hypersensitive to this medication.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Should not take if you have slowed central nervous system activity due to sleeping medication, circulatory system collapse, or abnormal bone marrow or blood condition.
  • May mask symptoms of brain tumor or intestinal obstruction. If you have or had: brain tumor, breast cancer, convulsive disorders, glaucoma, intestinal blockage, or heart disease, or were exposed to extreme heat, or are recovering from alcohol addiction, doctor will prescribe cautiously.
  • May cause tardive dyskinesia — involuntary muscle spasms and twitches in face and body, which can be permanent

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Navane side effects, please contact your healthcare provider