Generic name: Methazolamide.

Neptazane is a carbonic anhydrase inhibitor. It decreases the formation of the watery fluid of the eye, nereby lowering intraocular pressure. 

Quick Facts About Neptazane


Used to treat chronic open-angle glaucoma. Also used in acute angle-closure glaucoma when eye pressure must be lowered before surgery.

Neptazane Dosage

Take exactly as prescribed; doctor may prescribe other medications with Neptazane.

  • Usual adult dose: 50 to 100 milligrams taken 2 to 3 times per day.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. If so, skip missed dose; go back to regular schedule. Do not double doses.

Neptazane Side Effects

Overdose symptoms:

no specific information available. However, if you suspect an overdose, immediately seek medical attention.

More common side effects: confusion; depression; diarrhea; dizziness; drowsiness; excessive urination; fatigue; fever; general feeling of not being well; headache; hearing problems; loss of appetite; nausea and vomiting; rash; ringing in ears; severe allergic reaction; taste changes; temporary nearsightedness; tingling in fingers, toes, hands, or feet.

Less common Neptazane side effects: black or tarry stools, blood in urine, convulsions, hives, increased sensitivity to light, kidney stones, paralysis.


Inform your doctor before combining Neptazane with:

high doses of aspirin taken at the same time; can cause loss of appetite, rapid breathing, lethargy, coma, and even death. Using with steroids may lower potassium levels.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • May cause allergic reactions including fever, rash, redness and peeling of skin, hives, difficulty breathing, serious skin and blood disorders, and even death. Doctor should monitor blood during Neptazane therapy. Immediately contact your doctor if you experience any of these symptoms.
  • Should not use if you have kidney or liver disease, adrenal gland disorders, or low sodium or potassium levels.
  • May aggravate acidosis (too much acid in the blood).
  • Doctor will prescribe with caution if you have emphysema or lung blockage.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Neptazane side effects, please contact your healthcare provider