Generic name: Labetalol hydrochloride.

Other brand names: Trandate.

Normodyne is an alpha/beta-adrenergic blocking agent. It works by blocking impulses along certain nerve pathways. 

Quick Facts About Normodyne


Used to treat high blood pressure.

Normodyne Dosage

Can take with or without food; level of Normodyne absorbed into the bloodstream is increased by food. Take exactly as prescribed, even if symptoms disappear. Adhere to dosage schedule for Normodyne to be effective; missing doses may worsen symptoms. May take several weeks to observe full effects of medication.

  • Usual adult dose: 100 milligrams taken 2 times per day, alone or with a diuretic medication. Initial dose may be given in doctor’s office, with 1-to-3-hour observation period. Doctor may increase dose after 2 or 3 days of monitoring blood pressure. Regular dose ranges — 200 to 400 milligrams taken 2 times per day. Seniors — dose determined based on individual needs.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. If so, skip missed dose; go back to regular schedule. Do not double doses.

Normodyne Side Effects

Overdose symptoms:

dizziness when standing up, severely low blood pressure, severely slow heartbeat. If you suspect an overdose, immediately seek medical attention.

More common side effects: dizziness, fatigue, indigestion, nausea, stuffy nose.

Less common or rare Normodyne side effects: anaphylaxis (severe allergic reaction); angioedema (swelling of face, lips, tongue, and throat; difficulty swallowing); change in taste; depression; diarrhea; difficulty urinating; dizziness upon standing up; drowsiness; dry eyes; ejaculation failure; fainting; fluid retention; hair loss; headache; heart block; hives; impotence; increased sweating; itching; low blood pressure; lupus erythematosus; muscle cramps; rash; shortness of breath; slow heartbeat; tingling or pins and needles; tingling scalp; vertigo; vision changes; weakness; wheezing; vomiting; yellow eyes and skin.


Inform your doctor before combining Normodyne with:

airway-opening medications such as Proventil and Ventolin: antidepressants such as Elavil; cimetidine (Tagamet); diabetes medications such as Micronase; epinephrine (EpiPen); insulin; nitroglycerin products such as Transderm-Nitro; nonsteroidal antiinflammatory medications such as Advil and Motrin; ritrodrine (Yutopar); verapamil (Calan).

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant.

Use with caution for seniors; dose based on individual needs.

Not generally prescribed for children.

  • If you stop medication abruptly, can cause chest pain or heart attack.
  • Should not take if you have: bronchial asthma, congestive heart failure, heart block, inadequate blood supply to the circulatory system, severely slow heartbeat, or other conditions causing severe and continued low blood pressure.
  • In rare cases has caused severe liver damage; symptoms include: itching, dark urine, continuing loss of appetite, yellow eyes and skin, unexplained flu-like symptoms.
  • Use with caution if you have a history of: asthma, chronic bronchitis, congestive heart failure, emphysema, kidney or liver disease.
  • If susceptible to severe allergic reactions, may experience severe reaction to Normodyne.
  • Symptoms of low blood sugar may be masked, or blood sugar levels may be altered during Normodyne therapy.
  • Inform your dentist or doctor in the event of a medical emergency or before surgery or dental treatment.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Normodyne side effects, please contact your healthcare provider