Generic name: Chlorhexidine gluconate.

Peridex is an oral disinfectant. It is thought to eliminate bacteria which cause dental plaque. 

Quick Facts About Peridex


Used to treat gingivitis (red and swollen gums) and to control gum bleeding caused by gingivitis.

Peridex Dosage

Should have a dental cleaning prior to Peridex treatment. When using Peridex, do not dilute and do not eat or drink for several hours after using medication.

  • Usual adult dose: 1/2 fluid ounce, undiluted, to rinse with for 30 seconds in the morning and evening after brushing teeth. Spit out after rinsing and never swallow.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: resume schedule after next brushing.

Peridex Side Effects

Overdose symptoms:

(for accidental child overdose) –  signs of alcohol intoxication (slurred speech, staggering, or sleepiness), upset stomach, nausea. If you suspect an overdose, immediately seek medical attention.

More common side effects: change in taste; increase in plaque; staining of teeth, mouth, tooth fillings, dentures, or other mouth appliances.

Less common Peridex side effects: irritation of the mouth, scaling of lining of the mouth.


No Peridex drug interactions reported.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Peridex appears in breast milk.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children 2 years and older.

  • Do not use if sensitive to or allergic to Peridex unless directed by your doctor.
  • May stain front-tooth fillings, especially those with a rough surface. Is usually removed with a professional dental cleaning.
  • Not for treating periodontal disease.
  • May cause excess tartar buildup; have teeth cleaned every 6 months to avoid buildup.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Peridex side effects, please contact your healthcare provider