Generic name: Dexchlorpheniramine maleate.

Other brand names: Dexchlor, Poladex, Polargen.

Polaramine is an antihistamine. Antihistamines block the effects of histamine, a body chemical that causes swelling and itching.

Quick Facts About Polaramine


Used to treat allergy symptoms including: nasal stuffiness and inflammation, and eye irritation caused by hay fever and other allergies; itching, swelling, and redness from hives and other rashes; allergic reactions to blood transfusions; and in combination with other medications, anaphylactic shock (severe allergic reaction).

Polaramine Dosage

Take exactly as prescribed.

  • Usual adult dose: Polaramine Repetabs Tablets — one 4 or 6 milligram tablet at bedtime or every 8 to 10 hours during the day. Polaramine Tablets — 1 tablet every 4 to 6 hours. Polaramine Syrup — 1 teaspoon (2 milligrams) every 4 to 6 hours.
  • Usual child dose: Polaramine Repetabs Tablets — children 12 years and over are prescribed adult dosage. Children ages 6 to 11 — one 4 milligram tablet per day at bedtime. Polaramine Tablets — children 12 years and older are prescribed adult dose. Children ages 6 to 11 — 1/2 tablet every 4 to 6 hours. Children 2 to 5 years — 1/4 tablet every 4 to 6 hours. Polaramine Syrup — children 12 years and older are prescribed adult dose. Children 6 to 11 years — 1/4 teaspoon (1 milligram) every 4 to 6 hours. Children 2 to 5 years — 1/4 teaspoon (1/2 milligram) every 4 to 6 hours.
  • Missed dose: if taking on a regular schedule — take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Polaramine Side Effects

Overdose symptoms:

blurred vision, cardiovascular collapse, convulsions, decreased alertness, difficulty sleeping, dizziness, hallucinations, lack of muscle coordination, low blood pressure, ringing in ears, sedation, temporary failure to breathe, tremors. Symptoms in children: dry mouth, extremely high body temperature, fixed or dilated pupils, flushing, stimulation, stomach and intestinal problems. If you suspect an overdose, immediately seek medical attention.

More common side effects: mild to moderate drowsiness, thickening of mucus.

Less common or rare Polaramine side effects: anaphylactic shock (severe allergic reaction); blurred vision; chest congestion; chills; confusion; constipation; convulsions; diarrhea; difficulty sleeping; difficulty urinating; disturbed coordination; dizziness; dry mouth, nose, and throat; early menstruation; excessive perspiration; excitement (especially in children); extreme fatigue; exaggerated sense of well-being; fever; frequent urination; headache; hives; hysteria; irritability; loss of appetite; low blood pressure; nausea; nervousness; nightmares; painful urination; pounding heartbeat; premature heart contractions; rapid heartbeat; rash; restlessness; ringing in ears; sedation; sensitivity to sun; sore throat; stomach upset or pain; stuffy nose; sweating; tightness in chest; tingling or pins and needles; tiredness; tremor; unusual bleeding or bruising; urinary retention; vertigo; vomiting; weakness; wheezing.


Inform your doctor before combining Polaramine with:

antidepressants such as Elavil and Tofranil, blood thinners such as Coumadin, sedatives such as Nembutal and Seconal, tranquilizers such as Xanax and Valium. May hide effects of aspirin if taking aspirin in large doses. Do not take Polaramine if you are taking MAO inhibitors such as Parnate and Nardil; may cause extremely low blood pressure.

Avoid alcohol during Polaramine therapy. 

Special Cautions

Should not be used during third trimester. If pregnant or planning to become pregnant, inform your doctor immediately. Appears in breast milk; could affect a nursing infant

May cause dizziness and low blood pressure in seniors.

Follow doctor’s instructions carefully for children. Do not administer to premature infants or newborns.

  • Do not take if sensitive to or allergic to this or similar medications.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Use with caution if you have: glaucoma, obstructive peptic ulcer or other stomach problems, symptoms of enlarged prostate, difficulty urinating, history of bronchial asthma, overactive thyroid, heart disease, circulatory problems, or high blood pressure.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Polaramine side effects, please contact your healthcare provider