Generic name: Dipivefrin hydrochloride.

Propine is an antiglaucoma agent. It decreases eye fluid production and enhances outflow. It is a “prodrug”, a drug that is not active by itself but is converted in the body to an active form.

Quick Facts About Propine


Used to treat chronic open-angle glaucoma.

Propine Dosage

Use exactly as prescribed, and use regularly. Will most likely continue treatment for life, as there is no cure for glaucoma. Wash hands before and after use, and do not touch the applicator to your eye or any other surface.

  • Usual adult dose: 1 drop in eye(s) every 12 hours. May take 1/2 hour for medication to work, will experience maximum results within 1 hour.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Propine Side Effects

Overdose symptoms:

no specific information available. If you suspect an overdose, immediately seek medical attention.

More common side effects: burning and stinging, red eyes.

Less common or rare Propine side effects: allergic reactions, change in heart rhythm, conjunctivitis, extreme dilation of pupils, increased heart rate or blood pressure, increased sensitivity to light.


No significant Propine drug interactions reported.

No known food/other substance interactions.

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not generally prescribed for children.

  • Do not use if you have narrow-angle glaucoma unless directed by your doctor.
  • May blur vision or cause other problems for a short while. Do not drive, operate machinery or participate in any other hazardous activity.
  • If sensitive to or allergic to Propine, should not use.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Propine side effects, please contact your healthcare provider