Generic name: Fluoxetine hydrochloride.

Prozac is a cyclic antidepressant. It increases the concentration of certain chemicals necessary for nerve transmission in the brain.

Quick Facts About Prozac


Used to treat major depression — continuing depression that interferes with daily functioning, such as changes in appetite, sleep habits, and mind or body coordination, decreased sex drive, increased fatigue, feelings of guilt or worthlessness, difficulty concentrating, slowed thinking, suicidal thoughts. Also used to treat obesity, eating disorders (including bulimia), and obsessive-compulsive disorders.

Prozac Dosage

Take exactly as prescribed, and at the same time each day.

  • Usual adult dose: 20 milligrams per day, taken in the morning. Doses over 20 milligrams should be divided into 2 doses. Total maximum dose is 80 milligrams per day. For individuals with kidney or liver disease — may have dose adjusted by doctor. Seniors — dose is individualized.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless several hours have passed. In that case, do not take missed dose: go back to regular schedule. Do not double doses.

Prozac Side Effects

Overdose symptoms:

agitation, nausea, restlessness, vomiting. If you suspect an overdose, immediately seek medical attention.

More common side effects: abnormal dreams, agitation, anxiety, bronchitis, chills, diarrhea, dizziness, drowsiness and fatigue, hay fever, inability to fall or stay asleep, increased appetite, lack or loss of appetite, light-headedness, nausea, nervousness, sweating, tremors, weakness, weight loss, yawning.

Less common Prozac side effects: abnormal ejaculation, abnormal gait, abnormal stoppage of menstrual flow, acne, amnesia, apathy, arthritis, asthma, belching, bone pain, breast cysts, breast pain, brief loss of consciousness, bursitis, chills and fever, conjunctivitis (pink eye), convulsions, dark or tarry stool, difficulty swallowing, dilation of pupils, dimness of vision, dry skin, ear pain, eye pain, exaggerated feeling of wellbeing, excessive bleeding, facial swelling due to fluid retention, fluid retention, hair loss, hallucinations, hangover effect, hiccups, high or low blood pressure, hives, hostility, impotence, increased sex drive, inflammation of the esophagus, inflammation of the gums, inflammation of the stomach lining, inflammation of the tongue, inflammation of the vagina, intolerance of light, involuntary movement, irrational ideas, irregular heartbeat, jaw or neck pain, lack of muscle coordination, low blood pressure upon standing, low blood sugar, migraine, mouth inflammation, neck pain and rigidit, nosebleed, ovarian disorders, paranoid reaction, pelvic pain, pneumonia, rapid breathing, rapid heartbeat, ringing in ears, severe chest pain, skin inflammation, skin rash, thirst, twitching, uncoordinated movements, urinary disorders, vague feeling of bodily discomfort, vertigo, weight gain. Rare side effects: antisocial behavior, blood in urine, bloody diarrhea, bone disease, breast enlargement, cataracts, colitis, coma, deafness, decreased reflexes, dehydration, double vision, drooping of eyelids, duodenal ulcer, enlarged abdomen, enlargement of liver, enlargement or increased activity of thyroid gland, excess growth of coarse hair on face and chest, excess uterine or vaginal bleeding, extreme muscle tension, eye bleeding, female milk production, fluid accumulation and swelling in the head, fluid buildup in larynx and lungs, gallstones, glaucoma, gout, heart attack, hepatitis, high blood sugar, hysteria, inability to control bowel movements, increased salivation, inflammation of eyes and eyelids, inflammation of gallbladder, inflammation of small intestine, inflammation of tissue below the skin, kidney disorders, king inflammation, menstrual disorders, miscarriage, mouth sores, muscle inflammation or bleeding, muscle spasms, painful sexual intercourse for women, psoriasis, rashes, reddish or purplish skin spots, reduction of body temperature, rheumatoid arthritis, seborrhea, shingles, skin discoloration, skin inflammation and disorders, slowing of heart rate, slurred speech, spitting blood, stomach ulcer, stupor, suicidal thoughts, taste loss, temporary cessation of breathing, tingling sensation around mouth, tongue discoloration and swelling, urinary tract disorders, vomiting blood, yellow eyes and skin.


Do not take Prozac if you are using а MAO inhibitor such as Nardil and Parnate, may cause fatal reaction.

Inform your doctor before combining Prozac with:

carbamazepine (Tegretol), diazepam (Valium), digitalis (Lanoxin), flecainide (Tambocor), lithium (Eskalith), medications that act on the central nervous system such as Xanax and Valium, other antidepressants (Elavil), tryptophan, vinblastine (Velban), warfarin (Coumadin). Also notify your doctor of any other prescription or nonprescription medications you are taking.

Do not drink alcohol while taking Prozac. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Dose is individualized for seniors.

Not generally prescribed for children.

  • Do not take if you have recently had a heart attack, have kidney or liver disease, or diabetes.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • If sensitive to or allergic to this or similar medications, should not take. Immediately stop taking Prozac if you experience skin rash or hives.
  • Use with caution if you have a history of seizures.
  • Inform your doctor if you experience dizziness or actually faint when standing from sitting or lying down.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Prozac side effects, please contact your healthcare provider