Generic name: Tolcapone.

Tasmar is an antiparkinsonian. It enhances the effectiveness of the Parkinson’s medication carbidopa/levodopa (Sinemet) by inhibiting the breakdown of levodopa so that it remains in the body longer. 

Quick Facts About Tasmar


Used as an adjunct to carbidopa/levodopa (Sinemet) in the treatment of Parkinson’s disease.

Tasmar Dosage

Take exactly as prescribed in combination with Sinemet Take with or without food.

  • Usual adult dose: 100 to 200 milligrams 3 times per day. Doctor may lower Sinemet dosage for best Combination of medications.
  • Usual child dose: not generally prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Tasmar Side Effects

Overdose symptoms:

dizziness, nausea, vomiting. If you suspect an overdose, immediately seek medical attention.

More common side effects: abnormal jerky movements, abdominal pain, accidental falling and injury anorexia, confusion, constipation, diarrhea, difficulty moving, difficulty sleeping, dizziness when rising from a sitting or lying position, excessive dreaming, extreme drowsiness, dry mouth, fatigue, headache, hallucination, muscle cramps, nausea, sweating, upper respiratory tract infection, urinary tract infection, urine discoloration, vomiting.

Less common Tasmar side effects: abnormal walking, anxiety, blurred vision, bone fractures, frequent urination, lethargy, pain in joints or limbs, partial paralysis, pneumonia, sinusitis, swelling of arms and legs, taste changes, weakness, weight loss. Rare side effects may occur in any system of the body.


Inform your doctor before combining Tasmar with:

isoproterenol/pheylephrine (Duo-Medihaler); MAO inhibitors such as phenelzine (Nardil) and tranylcypromine (Parnate); methyldopa (Aldomet); tolbutamide (Orinase); warfarin (Coumadin). Avoid any medications containing cytochrome, dobutamine, apomorphine, or desipramine.

No known food/other substance interactions. 

Special Cautions

Concurrent Sinemet medication may cause fetal injury. If pregnant, planning to become pregnant, or breastfeeding, inform your doctor immediately.

Seniors are more likely to develop hallucinations than younger patients, and less likely to develop abnormal jerky movement

Not generally prescribed for children.

  • Inform your doctor before treatment if you have liver disease (especially cirrhosis).
  • May impair your ability to drive a car or operate machinery. Do not take part in any activity that requires mental alertness until adjusted to medication.
  • Women experience more side effects than men, and should be closely monitored.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Tasmar side effects, please contact your healthcare provider