Generic name: Tobramycin.

Tobrex is an aminoglycoside ophthalmic antibiotic. It prevents the growth and multiplication of infecting bacteria. 

Quick Facts About Tobrex


Used to treat bacterial infections of the eye.

Tobrex Dosage

Apply eye drops and ointment exactly as prescribed. Use Tobrex for entire time prescribed, even if symptoms disappear.

  • Usual adult dose: solution — 1 or 2 drops into affected eye every 4 hours for mild to moderate infection. 2 drops every hour until improvement for severe infection. Gradually reduce dose before stopping. Ointment — 1/2-inch ribbon into affected eye 2 or 3 times per day for mild to moderate infection; 1/2-inch ribbon into affected eye every 3 or 4 hours until improvement for severe infection. Gradually reduce dose before stopping.
  • Usual child dose: individually tailored by doctor.
  • Missed dose: apply as soon as possible, unless it is the next day. In that case, do not take missed dose; go back to regular schedule.

Tobrex Side Effects

Overdose symptoms:

corneal redness and inflammation, excessive eye tearing, lid itching and swelling. If you suspect an overdose, immediately seek medical attention.

Side effects: abnormal redness of eye tissue, allergic reactions, lid itching, lid swelling.

No known less common or rare Tobrex side effects.


Inform your doctor before combining Tobrex with other prescription eye antibiotics.

No known food/other substance interactions. 

Special Cautions

If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk could affect a nursing infant.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children.

  • Avoid if sensitive to or allergic to Tobrex or any of its ingredients. If you experience allergic reaction, stop using and immediately contact your doctor.
  • May cause a secondary infection not treatable by Tobrex.
  • Ophthalmic ointments can slow healing of corneal wounds.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Tobrex side effects, please contact your healthcare provider