Generic name: Desonide.

Other brand name: DesOwen.

Tridesilon is a topical adrenocorticoid/anti-inflammatory. It interferes with the natural body mechanisms that produce rash, itching, or inflammation.

Quick Facts About Tridesilon


Used to treat the itching and inflammation of a variety of skin disorders.

Tridesilon Dosage

Use exactly as prescribed. For use on the skin only; keep away from eyes. Use sparingly and not for prolonged periods of time. Do not wrap treated area in bandages unless specifically directed by your doctor.

  • Usual adult dose: apply thin film to affected area 2 to 4 times per day. Doctor may prescribe bandage if using for psoriasis or other conditions that do not respond well to medication.
  • Usual child dose:same as adult dose.
  • Missed dose: apply as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses.

Tridesilon Side Effects

Overdose symptoms:

increase in blood sugar and Cushing’s syndrome (moon-shaped face, emotional disturbances, high blood pressure, weight gain, and in women, baldness or growth of body or facial hair) or diabetes. If you suspect an overdose, immediately seek medical attention.

Side effects: acne, additional infections, allergic reactions of the skin, burning of the skin, dryness, excessive growth of hair, irritation, itching, loss of skin pigmentation, prickly heat, rash, skin inflammation around the mouth, skin softening, stretch marks. Side effects in children: delayed weight gain, headaches, slowed growth.

No known less common or rare Tridesilon side effects.


No Tridesilon drug interactions reported.

No known food/other substance interactions.

Special Cautions

Powerful steroids have caused birth defects in animak. Tridesilon should not be used in large amounts or over large parts of the body by pregnant women. If pregnant or planning to become pregnant, inform your doctor immediately. Not known if Tridesilon appears in breast milk.

No special precautions apply to seniors.

Follow doctor’s instructions carefully for children. Avoid covering treated area with plastic pants or waterproof diapers.

  • Avoid if sensitive to or allergic to Tridesilon.
  • Inform your doctor if an irritation develops.

Note: provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Tridesilon side effects, please contact your healthcare provider