Generic name: Capecitabine.

Xeloda is a fluoropyrimidine carbamate/anticancer medication. It is converted in the body to the substance 5-fluorouracil, which can kill cancer cells and decreases the size of the tumor.

Quick Facts About Xeloda


Used to treat breast cancer that has spread to other parts of the body and does not respond to certain other chemotherapy treatments.

Xeloda Dosage

Take with water at the end of your morning and evening meals. Xeloda is supplied in 150-milligram and 500-milligram tablets, which will be combined to form appropriate dose by doctor.

  • Usual adult dose: 2500 milligrams per day divided into 2 doses for 2 weeks, followed by a 1-week rest period before resuming cycle.
  • Usual child dose: not prescribed for children.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, inform doctor, do not take missed dose; go back to regular schedule. Do not double doses.

Xeloda Side Effects

Overdose symptoms:

nausea, vomiting, diarrhea, gastrointestinal irritation and bleeding, and bone marrow depression. If you suspect an overdose, immediately seek medical attention.

More common side effects: abdominal pain, appetite loss, constipation, dehydration, diarrhea, dizziness, dry or itchy skin, headache, fever, nausea, rash, sores in mouth and throat, tiredness, vomiting, weakness. May also cause hand-and-foot syndrome (palms of the hands or soles of the feet tingle, become numb, painful, swollen, or red). Side effects are usually mileter than with other anticancer treatments.

Rare Xeloda side effects may affect any system in the body.


Inform your doctor before combining Xeloda with:

antacids such as Maalox; leucovorin (Citrocovorin Calcium, Folinic Acid, and others); paclitaxel (Taxol) and other anticancer therapies with similar side effects.

No known food/other substance interactions.

Special Cautions

May cause fetal injury. If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Seniors may be more sensitive to effects of 5-FU and should be closely monitored. Also more likely to experience diarrhea, nausea, and vomiting.

Not prescribed for children.

  • Should not use if sensitive to or allergic to 5-fluorouracil.
  • Stop treatment immediately and contact your doctor if you experience: more than 4 bowel movements each day or any diarrhea at night; repeated vomiting; loss of appetite; stomatitis (pain, redness, swelling or sores in your mouth); hand-and-foot syndrome (pain, swelling or redness of hands and/or feet); a fever of 100.5° F or greater, or other evidence of infection. Doctor may recommend temporarily stopping therapy.
  • Relieve mild to moderate diarrhea with Imodium.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Xeloda side effects, please contact your healthcare provider