Generic name: Zolmitriptan.

Zomig is an anti-migraine. It is thought to work by slowing nerve activity in the brain.

Quick Facts About Zomig


Used to treat severe migraines. Will not prevent or reduce migraine attacks.

Zomig Dosage

Take as soon as migraine symptoms begin or at any  time during attack. May take second dose after 2 hours if symptoms are not relieved.

  • Usual adult dose: 1.25 to 5 milligrams as needed.
  • Usual child dose: not prescribed for children.
  • Missed dose: do not take on a regular basis. Take only during an attack.

Zomig Side Effects

Overdose symptoms:

none reported; however, if you suspect an overdose, immediately seek medical attention.

More common side effects: burning or warmth, dizziness, fainting, tightness in chest, jaw, or neck, tiredness. Side effects are usually mild and well tolerated.

Less common Zomig side effects: agitation, allergic reaction, back pain, bronchitis or bronchial spasm, changes in appetite, chest pressure or tightness, dry mouth, difficulty swallowing, emotional instability, eye problems, fainting, fever, general feeling of ill health, hiccups, increased sensitivity to sounds or smells, insomnia, irregular heart rhythms and other heart problems, irritation of mouth or stomach, laryngitis, leg cramp, muscle ache and weakness, nausea, nosebleeds, reduced sensation, sensitivity to bright light, skin problems including rash, sweating, swelling, tendonitis, thirst, urinary tract problems, yawning. Rare side effects: arthritis, blood cell abnormalities, blood in vomit or stool, bruising, constipation, difficulty breathing, double vision, hallucinations, high blood sugar levels, memory loss, menstrual pain, miscarriage, pancreas irritation, poor blood flow, stiff muscles, tearing, uncontrolled movement, vein irritation, weakness.


Inform your doctor before combining Zomig with:

Do not combine Zomig with sumatriptan (Imitrex) or  any similar anti-migraine medication. Inform your doctor before combining Zomig with: acetaminophen; cimetidine (Tagamet); ergotamine (Cafergot) or other ergot-containing medications such as Ergostat; oral contraceptives; propranolol (inderal); SSRI antidepressants such as Prozac, Luvox, Paxil, and Zoloft. Wait at least 2 weeks between taking Zomig and MAO inhibitors.

No known food/other substance interactions.

Special Cautions

Effects of Zomig on pregnant women not known, but may cause harm to fetus. If pregnant, planning to become pregnant, or breastfeeding, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

No special precautions apply to seniors.

Not prescribed for children.

  • If allergic to this or similar medications, should not use.
  • Should not use if you have: heart disease, including angina, history of heart attack, irregular heartbeat, shortness of breath: uncontrolled blood pressure; or if taking a medication containing ergotamine.
  • Use with caution if you have: liver or kidney disease, diabetes, high cholesterol levels, obesity, a history of smoking.
  • May cause drowsiness and impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • If you develop tightness in chest or throat, shortness of breath, heart throbbing, or especially chest pain that does not go away, call your doctor immediately.
  • Should have your eyes examined regularly and report any changes in vision to your doctor.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Zomig side effects, please contact your healthcare provider