Generic name: Olanzapine.

Zyprexa is an antipsychotic. It works by increasing the levels of certain chemicals in the brain.

Quick Facts About Zyprexa


Used to manage chronic psychotic disorders.

Zyprexa Dosage

Take with or without food, at the same time every day.

  • Usual adult dose: 5 to 10 milligrams once per day. Doctor may gradually increase dose up to 20 milligrams per day.
  • Usual child dose: not generally prescribed for children under 18 years.
  • Missed dose: take as soon as possible, unless almost time for next dose. In that case, do not take missed dose; go back to regular schedule. Do not double doses. Inform your doctor if several regular doses are missed.

Zyprexa Side Effects

Overdose symptoms:

drowsiness, slurred speech. If you suspect an overdose, immediately seek medical attention.

More common side effects: agitation, dizziness, fever, headache, hostility, insomnia, nervousness, runny nose, tiredness.

Less common Zyprexa side effects: abdominal pain, anxiety, body pains, constipation, cough or sore throat, difficulty speaking, dizziness or fainting when rising from a sitting or lying position, dry mouth, euphoria, feeling of restlessness, fever, increased appetite, low blood pressure, memory loss, muscle stiffness, personality changes, rapid heartbeat, swelling of arms or legs, symptoms of premenstrual syndrome (PMS), tremors, twitching, vision problems, weight gain. May cause rare side effects in any system of the body.


Inform your doctor before combining Zyprexa with:

blood-pressure-lowering medications; carbamazepine (Tegretol); or any other medications.

Do not drink alcohol or use other central nervous system depressants while taking Zyprexa.

Special Cautions

May cause harm to fetus. If pregnant or planning to become pregnant, inform your doctor immediately. May appear in breast milk; could affect a nursing infant.

Seniors may be prescribed a lower dose.

Not generally prescribed for children.

  • At risk for neuroleptic malignant syndrome (NMS), which may be fatal. Symptoms: extremely high body temperature, rigid muscles, mental changes, irregular pulse or blood pressure, rapid heartbeat, sweating, and changes in heart rhythm.
  • May impair your ability to drive a car or operate machinery. Do not take part in any activity that requires alertness.
  • Ask your doctor about the risk of tardive dyskinesia, a condition marked by involuntary muscle movements.
  • May cause swallowing problems. Can also cause dry mouth, which should be monitored with regular dental checkups.
  • Use with caution if you have a history of liver disease or smoking.
  • Sunlight and heat sensitivity may be increased. Take care to avoid dehydration.
  • Possibility of a suicide attempt exists in any person with schizophrenia. Close supervision and prescriptions in small amounts should accompany drug therapy to reduce risk of overdose.


HealthSurvey.org provides accurate and independent information prescription pills, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. If you have questions about  dosage, or Zyprexa side effects, please contact your healthcare provider.